Objective  To evaluate the repeatability and accuracy of corneal parameters in post-laser in situ keratomileusis （LASIK） eyes obtained by RTVue Fourier-domain optical coherence topography （FD-OCT）. Methods  In this prospective study， 58 right eyes of 58 persons who agreed to undergo LASIK were included. Subjective refractions were performed before LASIK and 3 months after LASIK. IOL Master was used to evaluate corneal power before LASIK. Three months after LASIK， RTVue FD-OCT was used to evaluate the anterior corneal curvature in a 3 mm central zone （Ranterior）， posterior corneal curvature in a 3 mm zone （Rposterior）， the ratio of posterior and anterior curvature （Rposterior/ Ranterior）， central corneal thickness （CCT）， total corneal power （Knet）， simulated corneal power （SimK）， anterior corneal power （Kanterior）， and posterior corneal power （Kposterior）. Km was obtained with IOL Master 3 months after the surgery. Kchm was calculated from the patient′s clinical history. Repeatability of corneal parameters was assessed using the coefficient of variation （CV）， Cronbach′s alpha， and intra-class correlation coefficient （ICC）. Bonferroni corrected multiple comparisons analyzed the differences between SimK， Knet， Km and Kchm. A Pearson correlation analyzed the correlations between SimK， Knet， Km and Kchm. Bland-Altman plots analyzed the agreements between SimK and Kchm， Knet and Kchm， Km and Kchm， SimK and Knet， and SimK and Km. Results  The Ranterior， Rposterior， Rposterior/Ranterior， Kanterior， Kposterior， SimK， Knet and CCT were （8.560±0.292）mm， （6.525±0.159）mm， 0.763±0.024， （43.98±1.48）D， （-6.13±0.15）D， （39.47±1.33）D， （37.93±1.42）D and （451.81±33.91）μm， respectively. The CVs of all parameters were lower than 1%. Cronbach′s alpha and ICC were both higher than 0.9. SimK was （0.434±0.433）D higher than Kchm， Knet was （1.112±0.471）D lower than Kchm， Km was （0.334±0.379）D higher than Kchm， and SimK was （1.546±0.162）D higher than Kchm. All the differences were statistically significant （P<0.01）. SimK was （0.100±0.287）D higher than Km but the difference was not statistically significant. There were close correlations among SimK， Knet， Km and Kchm （r≥0.944， P<0.01）. The Bland-Altman analysis showed that the 95% limit of agreements between SimK and Kchm， Knet and Kchm， Km and Kchm， SimK and Knet， and SimK and Km were -0.41～1.28 D， -2.04～-1.11 D， -0.41～1.08 D， 1.23～1.86 D， -0.46～0.66 D， respectively. Conclusion  The RTVue Fourier-domain OCT had high repeatability on corneal curvature and CCT measurements in post-LASIK eyes. The SimK obtained by RTVue Fourier-domain OCT and IOL Master were 0.3 to 0.4 D higher than those obtained by clinical history. Knet may be a more accurate method to assess corneal power in post-LASIK eyes， but further clinical studies are needed for the prediction of post-LASIK intraocular lens power.