Objective To investigate the distribution of corneal thickness in myopic patients and the correlation of corneal thickness,refractive power and corneal curvature in myopia.Methods In a cross-sectional study,a total of 264 people (458 eyes) with myopia or myopic astigmatism were examined.One hundred twenty-two males and 142 females participated in the study.Corneal thickness was measured with a Pentacam system.Measurements were taken at the corneal apex,center point,thinnest point and the average value of all corneal thicknesses measured along 2 mm,4 mm,6 mm and 8 mm diameter rings with the apex location at its center.The average values for corneal thickness and curvature were recorded in an increasingly clockwise direction for the right eyes,and in a counterclockwise direction for the left eyes with the binocular temporal side set to 0°.The subjects were divided into three groups according to refractive error: the low myopia group (refractive error ＜-3.00 D),the moderate myopia group (refractive error ＞-3.00 D and ＜-6.00 D) and the high myopia group (refractive error ＞-6.00 D).ANOVA was used to analyze the differences for the three groups.The different points for corneal thickness between two groups were compared using an independent samples t test.Pearson correlation analysis was used to study the correlation of corneal thickness at different points and the relationship between corneal thickness and other factors.Results The mean values of corneal thickness at the corneal apex、center point and thinnest point were 529.58±22.38 μm,529.75±22.51 μm,and 527.78±22.7 μm.The greatest mean corneal thickness measured along the different diameter rings with the apex location at its center was always at 90 degrees and the mean values were 544.14±22.07 μm,583.15±24.72 μm,646.27±27.34 μm,and 716.52±27.70 μm.The lowest mean corneal thickness measured along the different diameter rings was at 315 degrees,315 degrees,337.5 degrees,and 342 degrees,and the values were 532.48±23.51 μm,549.24±26.97 μm,590.02±27.06 μm,and 657.37±32.03 μm.The mean values of corneal thickness at the corneal apex,center point and thinnest point were found to have a positive correlation between the left and tight eyes (r=0.768,0.548,0.671,P＜0.05).No significant correlation was found between corneal thickness and refractive error or tangential curvature (P＞O.05).Conclusion For the different diameter rings of corneal thickness in myopia,the peripheral corneal thickness values were lowest in the temporal and inferotemporal areas and greatest in the superior area.There was no relationship between corneal thickness and refractive error and corneal curvature.