Measurements of macular thickness changes after laser in situ keratomileusis using spectral domain optical coherence tomography
He Feng,Jin Yumei,Li Ying
Department of Ophthalmology， Peking Union Medical College Hospital， Peking Union Medical College， Chinese Academy of Medical Sciences， Beijing 100730， China
Objective To evaluate the effect of laser in situ keratomileusis （LASIK） for myopia as well as changes in the macula after surgery. Methods This was a prospective clinical study. Thirty patients （60 eyes） were selected randomly to undergo LASIK. Spectral domain optical coherence tomography （SD-OCT） was used to evaluate the total macular volume （TMV） and central retinal thickness （CRT） before surgery， and 10 days and 1 month after surgery. Data were analyzed by a repeated measures design and Pearson correlation analysis. Results Preoperatively， mean BCVA was -0.063±0.041， mean TMV was 7.31±0.31 mm3， and mean CRT was 220.3±21.1 μm. Ten days after surgery， mean BCVA was -0.043±0.081， mean TMV was 7.32±0.26 mm3， and mean CRT was 221.6±20.8 μm. One month after surgery， mean BCVA was -0.074±0.061， mean TMV was 7.35±0.29 mm3， and mean CRT was 219.8±22.9 μm. CRT had changed significantly 10 days postoperatively compared to preoperative measurements and postoperative measurements at 30 days （P＜0.05）， and TMV measurements changed significantly between 10 and 30 days postoperatively （P＜0.05）. The variations in TMV and CRT do not correlate significantly with the change in spherical equivalent. Conclusion Mild macular edema is common shortly after LASIK， but no association with a loss of BCVA has been established.
贺峰,金玉梅,李莹. 应用谱域OCT观察LASIK对黄斑区视网膜厚度的影响[J]. 中华眼视光学与视觉科学杂志, 2014, 16(11): 663-665.
He Feng,Jin Yumei,Li Ying. Measurements of macular thickness changes after laser in situ keratomileusis using spectral domain optical coherence tomography. Chinese Journal of Optometry Ophthalmology and Visual science, 2014, 16(11): 663-665. DOI: 10.3760/cma.j.issn.1674-845X.2014.11.006
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