高分辨弥散张量示踪用于鞍区肿瘤患者前视路的形态学研究

doi:10.3760/cma.j.cn115909-20190917-00252

Abstract
Figure/Table
References (15)
Related Citation (2)

Download: PDF (3120 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective: To investigate the imaging characteristics of the high-resolution diffusion tensor tracting (DTT) on the anterior visual pathway of sellar region tumors and its relationship with visual function and prognosis. Methods: This was a cases series study. From November 2015 to June 2017, 21 cases of sellar region tumors were surgically resected in the Fuzong Clinical Medical College of Fujian Medical University. High resolution diffusion tensor imaging (DTI) scans were performed one week before surgery and three months after surgery, and white matter fibers were reconstructed by DTT to observe the course and integrity of the fibers. A visual impairment score (VIS) was used to evaluate visual function. The data were analyzed by a Mann Whitney U test and Fisher exact probability test. Results: DTT could clearly show the interruption or integrity and sparseness or fullness of the white matter fiber bundle of the anterior visual pathway in 21 patients with sellar region tumor. It could also show the spatial position relationship between the white matter fiber bundle of the anterior visual pathway and sellar region tumor (8 cases of the interruption type, 13 cases of the continuity type). There was no significant difference in the vision score of patients with different shapes of white matter fiber bundle before surgery (Z=-0.679, P=0.497). Both the continuous type and interrupted type were related to the prognosis of visual function. The patients with an intact shape of the anterior visual tract had a better visual function status before surgery and better pre- and post-surgery at 4 months after the operation (P=0.014). Conclusions: High resolution DTT can visually display the shape of the anterior optic tract, and has a reference value for predicting the prognosis of visual function in patients with sellar region tumors.

Key words： high resolution diffusion tensor imaging diffusion tensor tracing sellar tumors anterior visual pathway visual impairment

Received: 17 September 2019

Fund:Startup Fund for Scientific Research, Fujian Medical University (2018QH1235); Science and Technology Fundation of Fujian Province (2018Y0067)

Corresponding Authors: Shousen Wang, Department of Neurosurgery, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou 350025, China (Email: wshsen@126.com)

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors

Cite this article:

URL:

https://www.cjoovs.com/EN/10.3760/cma.j.cn115909-20190917-00252 OR https://www.cjoovs.com/EN/Y2020/V22/I7/500

[1]	Kalita J, Soni N, Dubey D, et al. Evaluation of optic nerve functions in subacute combined degeneration using visual evoked potential and diffusion tensor imaging-a pilot study. Br J Radiol, 2018, 91(1091): 20180086. DOI: 10.1259/bjr.20180086.
[2]	黎连杰, 程兰, 鹿松松, 等. 正常成人前视路高分辨率弥散张量成像研究. 中华眼视光学与视觉科学杂志, 2018, 20(2): 114-120. DOI: 10.3760/cma.j.issn.1674-845X.2018.02.009.
[3]	Qiao N, Song M, Ye Z, et al. Deep learning for automatically visual evoked potential classification during surgical decompression of sellar region tumors. Transl Vis Sci Technol, 2019, 8(6): 21. DOI: 10.1167/tvst.8.6.21.
[4]	Fahlbusch R, Schott W. Pterional surgery of meningiomas of the tuberculum sellae and planum sphenoidale: Surgical results with special consideration of and endocrinological outcomes. J Neurosurg, 2002, 96(2): 235-243. DOI: 10.3171/ jns.2002.96.2.0235.
[5]	Jaeger W, Thomann H. German ophthalmological association recom Ⅱ lendacions for evaluation of reduced earning capacity caused by damage to vision.September 1981. Klin Monbl Augenheilkd, 1982, 180(3): 242-244. DOI: 10.1055/s-2008- 1055061.
[6]	Müslüman AM, Cansever T, Y?lmaz A, et al. Surgical results of large and giant pituitary adenomas with special consideration of ophthalmologic outcomes. World Neurosurg, 2011, 76(1-2): 141-148. DOI: 10.1016/j.wneu.2011.02.009.
[7]	Salma A. DTI in brain tumor surgery. J Neurosurg, 2015, 122(2): 474. DOI: 10.3171/2014.8.JNS141825.
[8]	Yamaguchi F, Ten H, Higuchi T, et al. An intraoperative motor tract positioning method in brain tumor surgery: Technical note. J Neurosurg, 2018, 129(3): 576-582. DOI: 10.3171/2017.5.JNS162978.
[9]	Soni N, Mehrotra A, Behari S, et al. Diffusion-tensor imaging and tractography application in pre-operative planning of intraaxial brain lesions. Cureus, 2017, 9(10): e1739. DOI: 10.7759/ cureus.1739.
[10]	Chen J, Zhu L, Li H, et al. Diffusion tensor imaging of occult injury of optic radiation following optic neuritis in multiple sclerosis. Exp Ther Med, 2016, 12(4): 2505-2510. DOI: 10.3892/etm.2016.3635.
[11]	Ma J, Su S, Yue S, et al. Preoperative visualization of cranial nerves in skull base tumor surgery using diffusion tensor imaging technology.Turk Neurosurg, 2016, 26(6): 805-812. DOI: 10.5137/1019-5149.JTN.13655-14.1.
[12]	Ge M, Li S, Wang L, et al. The role of diffusion tensor tractography in the surgical treatment of pediatric optic chiasmatic gliomas. J Neurooncol, 2015, 122(2): 357-366. DOI: 10.1007/s11060-015-1722-4.
[13]	Hajiabadi M, Alimohamadi M, Fahlbusch R. Decision making for patients with concomitant pituitary macroadenoma and ophthalmologic comorbidity: A clinical controversy. World Neurosurg, 2015, 84(1): 147-153. DOI: 10.1016/ j.wneu.2015.02.043.
[14]	Hajiabadi M, Samii M, Fahlbusch R, et al. A preliminary study of the clinical application of optic pathway diffusion tensor tractography insuprasellar tumor surgery: Preoperative, intraoperative, and postoperative assessment. J Neurosurg, 2016, 125(3): 759-765. DOI: 10.3171/2015.6.JNS1546.
[15]	Kida I, Ueguchi T, Matsuoka Y, et al. Comparison of diffusion-weighted imaging in the human brain using readout-segmented EPI and PROPELLER turbo spin echo with single-shot EPI at 7 T MRI. Invest Radiol, 2016, 51(7): 435-439. DOI: 10.1097/ RLI.0000000000000248.