早产儿出生后早期屈光系统发育及其影响因素

doi:10.3760/cma.j.cn115909-20190715-00196

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Abstract Objective: To study the development of the ocular biometry parameters and evaluate the relationship between axial length with gestational age and birth weight during 32 to 40 weeks of postnatal age. Methods: Premature infants screened for retinopathy of prematurity at Women's Hospital School of Medicine Zhejiang University and Eye Hospital, Wenzhou Medical University were included from March to December 2018. Infants were divided into groups based on age, gestational age (GA) <30 weeks and GA ≥30 weeks, and birth weight, birth weight (BW) <1 500 g and BW ≥1 500 g. They were examined between 32 to 40 weeks of postnatal age (PA). Anterior chamber depth (ACD), lens thickness (LT), vitreous length (VL) and axial length (AL) were measured with an A-scan biometer. BW and GA were recorded. Pearson correlation analysis was used to study the relationship between refractive system parameters and GA. The independent-samples t test was used to compare the AL between the two groups. Results: A total of 1 385 readings were recorded from 496 infants. The ACD (r=0.384, P<0.001), LT (r=0.295, P<0.001), VL (r=0.723, P<0.001) and AL (r=0.782, P<0.001) were all positively correlated with PA. There were no statistically significant differences in AL in the two groups from 32 to 40 weeks of PA (P>0.05). The average AL differed significantly from 38 to 40 weeks of PA in the two groups based on birth weight (t=2.195, P=0.030; t=2.504, P=0.015; t=1.989, P=0.048). Conclusions: In the early postnatal period of premature infants, gestational age has little effect on AL, however infants with low birth weight have a shorter AL.

Key words： ocular development birth weight gestational age infant, premature

Received: 15 July 2019

Fund:Medical Health Science and Technology Project of Zhejiang Provincial Health Commission (2019PY010); Basic Scientific Project of Wenzhou Science and Technology Commission (Y20180713)

Corresponding Authors: Lijun Shen, Eye Hospital, Wenzhou Medical University, Hangzhou 310000, China (Email: slj@mail.eye.ac.cn)

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https://www.cjoovs.com/EN/ 10.3760/cma.j.cn115909-20190715-00196 OR https://www.cjoovs.com/EN/Y2020/V22/I8/602

[1]	Goktas A, Sener EC, Sanac AS. An assessment of ocular morbidities of children born prematurely in early childhood. J Pediatr Ophthalmol Strabismus, 2012, 49(4): 236-241. DOI: 10.3928/01913913-20120207-02.
[2]	Deng Y, Yu CH, Ma YT, et al. Analysis of the clinical characteristics and refraction state in premature infants: A 10-year retrospective analysis. Int J Ophthalmol, 2019, 12(4): 621-626. DOI: 10.18240/ijo.2019.04.16.
[3]	毛剑波, 劳吉梦, 刘忱怡, 等. 早产儿出生后早期屈光状态及其影响因素. 中华眼视光学与视觉科学杂志, 2018, 20(10): 588-592. DOI: 10.3760/cma.j.issn.1674-845X.2018.10.003.
[4]	Chen TC, Tsai TH, Shih YF, et al. Long-term evaluation of refractive status and optical components in eyes of children born prematurely. Invest Ophthalmol Vis Sci, 2010, 51(12): 6140- 6148. DOI: 10.1167/iovs.10-5234.
[5]	Yu SJ, Liu GH, Liu Y, et al. The evolution of refractive status in Chinese infants during the first year of life and its affected factors. Int J Ophthalmol, 2017, 10(8): 1290-1294. DOI: 10.18240/ijo.2017.08.17.
[6]	Cook A, White S, Batterbury M, et al. Ocular growth and refractive error development in premature infants with or without retinopathy of prematurity. Invest Ophthalmol Vis Sci, 2008, 49(12): 5199-5207. DOI: 10.1167/iovs.06-0114.
[7]	Mao J, Lao J, Liu C, et al. Factors That influence refractive changes in the first year of myopia development in premature infants. J Ophthalmol, 2019, 2019: 7683749. DOI: 10.1155/ 2019/7683749.
[8]	Zhu X, Zhao R, Wang Y, et al. Refractive state and optical compositions of preterm children with and without retinopathy of prematurity in the first 6 years of life. Medicine (Baltimore), 2017, 96(45): e8565. DOI: 10.1097/MD.0000000000008565.
[9]	中华医学会眼科学分会眼底病学组. 中国早产儿视网膜病变筛查指南(2014年). 中华眼科杂志, 2014, 50(12): 933-935. DOI: 10.3760/cma.j.issn.0412-4081.2014.12.017.
[10]	?zdemir ?, ?zen Tunay Z, Ergintürk Acar D. Growth of biometric components and development of refractive errors in premature infants with or without retinopathy of prematurity. Turk J Med Sci, 2016, 46(2): 468-473. DOI: 10.3906/sag-1501-40.
[11]	?zdemir O, Tunay ZO, Acar DE, et al. The relationship of birth weight, gestational age, and postmenstrual age with ocular biometry parameters in premature infants. Arq Bras Oftalmol, 2015, 78(3): 146-149. DOI: 10.5935/0004-2749.20150038.
[12]	Laws DE, Haslett R, Ashby D, et al. Axial length biometry in infants with retinopathy of prematurity. Eye (Lond), 1994, 8 ( Pt 4): 427-430. DOI: 10.1038/eye.1994.101.
[13]	O'Brien C, Clark D. Ocular biometry in pre-term infants without retinopathy of prematurity. Eye (Lond), 1994, 8 (Pt 6): 662-665. DOI: 10.1038/eye.1994.163.
[14]	Ozdemir O, Tunay Z?, Petri?li IS, et al. Analysis of the horizontal corneal diameter, central corneal thickness, and axial length in premature infants. Arq Bras Oftalmol, 2014, 77(4): 225-227. DOI: 10.5935/0004-2749.20140058.
[15]	Ecsedy M, Kovacs I, Mihaltz K, et al. Scheimpflug imaging for long-term evaluation of optical components in Hungarian children with a history of preterm birth. J Pediatr Ophthalmol Strabismus, 2014, 51(4): 235-241. DOI: 10.3928/01913913- 20140521-04.
[16]	Ouyang LJ, Yin ZQ, Ke N, et al. Refractive status and optical components of premature babies with or without retinopathy of prematurity at 3-4 years old. Int J Clin Exp Med, 2015, 8(7): 11854-11861.
[17]	Fie? A, K?lb-Keerl R, Knuf M, et al. Axial length and anterior segment alterations in former preterm infants and full-term neonates analyzed with scheimpflug imaging. Cornea, 2017, 36(7): 821-827. DOI: 10.1097/ICO.0000000000001186.
[18]	Kardaras D, Papageorgiou E, Gaitana K, et al. The association between retinopathy of prematurity and ocular growth. Invest Ophthalmol Vis Sci, 2019, 60(1): 98-106. DOI: 10.1167/iovs. 18-24776.
[19]	?zdemir M, Koylu S. Ocular growth and morbidity in preterm children without retinopathy of prematurity. Jpn J Ophthalmol, 2009, 53(6): 623-628. DOI: 10.1007/s10384-009-0744-x.
[20]	Saw SM, Tong L, Chia KS, et al. The relation between birth size and the results of refractive error and biometry measurements in children. Br J Ophthalmol, 2004, 88(4): 538-542. DOI: 10.1136/ bjo.2003.025411.
[21]	Crofts BJ, King R, Johnson A. The contribution of low birth weight to severe vision loss in a geographically defined population. Br J Ophthalmol, 1998, 82(1): 9-13. DOI: 10.1136/ bjo.82.1.9.
[22]	Modrzejewska M, Grzesiak W, Karczewicz D, et al. Refractive status and ocular axial length in preterm infants without retinopathy of prematurity with regard to birth weight and gestational age. J Perinat Med, 2010, 38(3): 327-331. DOI: 10.1515/JPM.2010.018.