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| Distribution and Influencing Factors of Refractive Status in Term Neonates |
| Lihua Wang, Xinli Liu, Wei Chen, Suya Huang, Jianan Wang, Jingjing Feng, Huan Tong, Jianing Pu, Shanshan Xing |
| Department of Ophthalmology, Beijing Haidian Maternal and Child Health Hospital, Beijing 100080, China |
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Abstract Objective: To investigate the refractive status and its influencing factors in term neonates. Methods: In this cross-sectional study, a total of 379 full-term neonates (758 eyes) born in Haidian Maternal and Child Health Hospital were included using a simple random sampling method. Diopter was obtained by retinoscopy after cycloplegia, and the spherical equivalent (SE) was calculated. The SE of different genders, eyes type, age, gestational age, birth length, birth weight, ways of delivery, father's myopia, and mother's myopia were compared by Rank sum test, and correlations were analyzed by Spearman correlation analysis. The influencing factors of SE were analyzed using multiple linear regression. Results: The median SE of these infants was +3.00 (+1.75, +4.00) D. The SE of left eye was higher than the SE of right eye, showing statistically signifcant (Z=-2.70, P=0.007). In the frst month of birth, the age (days) was associated with SE (χ2=21.89, P<0.001). The SE in the macrosomia was higher than that in normal weight neonates (χ2=13.36, P=0.001). The SE in newborns whose parents were high myopia was significantly lower than those whose parents were low myopia or no myopia (χ2 =11.60, P=0.003; χ2=13.50, P=0.001). SE showed negative correlations with age (r=-0.12, P=0.001), father's myopia (r=-0.11, P=0.003), and mother's myopia (r=-0.11, P=0.002). SE showed positive correlations with birth weight (r=0.11, P=0.002). Regression analysis showed that the eye type, age, birth weight, father's myopia and mother's myopia were all associated with neonatal SE signifcantly (all P<0.05). Conclusions: The refractive status of term neonates was moderate to high hyperopia, and decreased within the frst month of birth. The SE of left eye was higher than that in right eye. Birth weight was positively correlated with SE, while parental myopia was negatively correlated with SE.
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Received: 10 April 2023
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| Fund:Health Development Scientific Research Cultivation Program of Beijing Haidian District (HP2022-10-103004) |
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Corresponding Authors:
Lihua Wang, Email: yanni6868@163.com
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