Objective To investigate the effects of wearing orthokeratology lenses on the magnitude of accommodative microfluctuations and accommodative lag. Methods In this cross-sectional study, 15 myopic subjects who wore orthokeratology lenses regularly and 15 myopic subjects who wore spectacles regularly were enrolled. Accommodative response (AR) was measured with an open field infrared autorefractor (WAM-5500) using an accommodative stimulus (AS) of 0~4 D. The magnitude of accommodative microfluctuations, accommodative lag, and accommodative error index (AEI) were calculated. The data from the two groups were analyzed by using an independent sample t test. Results With an AS of 0 D, 1 D, 2 D, 3 D and 4 D, the magnitudes of accommodative microfluctuations of the orthokeratology lens group were all larger than the spectacle group, and the differences were statistically significant (t=3.704, 3.277, 2.365, 2.179, 2.591, P<0.05). The accommodative lags of the orthokeratology lens group were smaller than the spectacle group. There were statistically significant differences with an AS of 2 D, 3 D and 4 D (t=-2.208, -2.244, -2.098, P<0.05), while there were no significant differences with an AS of 0 D and 1 D(t=-1.974, -1.758, P>0.05). The AEIs of the orthokeratology lens group were also smaller than the spectacle group, and the difference was statistically significant (t=-2.098, P<0.05). Conclusion Compared to spectacles, the magnitudes of accommodative microfluctuations were larger after myopes wore orthokeratology lenses, while the accommodative lags were smaller at high accommodative demands. This supports the claim that orthokeratology lenses can slow myopia progression.
吴从霞,毛欣杰,林惠玲,瞿佳. 角膜塑形镜对近视眼调节微波动幅度和调节滞后的影响[J]. 中华眼视光学与视觉科学杂志, 2013, 15(2): 75-78.
WU Cong-xia,MAO Xin-jie,LIN Hui-ling,QU Jia. An investigation of the effects of wearing orthokeratology lenses on the magnitude of accommodative microfluctuations and accommodative lag. Chinese Journal of Optometry Ophthalmology and Visual Science, 2013, 15(2): 75-78. DOI: 10.3760/cma.j.issn.1674-845X.2013.02.004
Norton TT, Siegwar JT Jr, Amedo AO. Effectiveness of hyperopic defocus, minimal defocus, or myopic defocus in competition with a myopiagenic stimulus in tree shrew eyes. Invest Ophthalmol Vis Sci,2006,47:4687-4699.
[2]
Collins M, Davis B, Wood J. Microfluctuations of steady-state accommodation and the cardiopulmonary system. Vision Res, 1995,35:2491-2502.
[3]
Langaas T, Riddell PM, Svarverud E, et al. Variability of the accommodation response in early onset myopia. Optom Vis Sci, 2008,85:37-48.
[4]
Wallman J, Winawer J. Homeostasis of eye growth and question of myopia. Neuron,2004,43:447-468.
[5]
Kakita T, Hiraoka T, Oshika T. Influence of overnight orthokeratology on axial elongation in children myopia. Invest Ophthalmol Vis Sci, 2011,52:2170-2174.
[6]
Cho P, Cheung SW. Retardation of myopia in Orthokeratology (ROMIO) study: a 2-year randomized clinical trial. Invest Ophthalmol Vis Sci,2012,53:7077-7085.
[7]
Hiraoka T, Kakita T, Okamota F, et al. Long-term effect of overnight orthokeratology on axial length elongation in childrenhood myopia: a 5-year follow-up study. Invest Ophthalmol Vis Sci,2012:53:3913-3919.
Day M, Strang NC, Seidel D, et al. Refractive groups differences in accommodation microfluctuations with changing accommodation stimulus. Ophthalmic Physiol Opt,2006,26:88-96.
[11]
Chauhan K, Charman WN. Single figure indices for the steady-state accommodative response. Ophthalmic Physiol Opt,1995,15:217-221.
[12]
Langaas T, Riddell PM. Accommodative instability: relationship to progression of early onset myopia. Clin Exp Optom,2012, 95:153-159.
[13]
Harb E, Thorn F, Troilo D. Characteristics of accommodative behavior during sustained reading in emmetropes and myopes. Vision Res,2006,46:2581-2592.
[14]
Hiraoka T, Okamoto C, Ishii Y, et al. Mesopic contrast sensitivity and ocular higher-order aberrations after overnight orthokeratology. Am J Ophthalmol,2008,145:645-655.
[15]
Hiraoka T, Okamoto C, Ishii Y, et al. Time course of change in ocular high-order aberrations and contrast sensitivity after overnight orthokeratology. Invest Ophthalmol Vis Sci,2008,49:4314-4320.
Gwiazda J, Thorn F, Held R. Accommodation, accommodation convergence, and response AC/A ratios before and at the onset of myopia in children. Optom Vis Sci,2005,82:273-278.
[20]
Allen PM, O′Leary DJ. Acommadation functions: co-dependency and relationship to refractive error. Vision Res,2006,46:491-505.