Abstract:Objective: To observe the effect of multifocal soft contact lenses on peripheral refraction and peripheralcorneal refractive power, and to investigate their correlation. Methods: This was a self-controlled study.Eighteen myopic adults were enrolled in Eye Hospital, Wenzhou Medical University from October 1,2020 to October 15, 2020. They underwent peripheral refraction and corneal refractive powermeasurements using infrared autorefractor and corneal topography when wearing monofocal soft contactlenses and multifocal soft contact lenses. The measurement range of peripheral refraction was from nasal30° to temporal 30° (at 5° intervals). The difference between peripheral refraction and central refractionwas identified as relative peripheral refraction (RPR). The nasal and temporal RPR was plotted on a curve,and the area under the curve was defined as the retinal area of relative peripheral refractive power (ARPR).The corresponding corneal coordinates of each fixation direction were calculated according to the Gaussianoptical system to obtain the total corneal refractive power of each point. The corneal relative peripheralrefractive power (CRPR) and corneal ARPR were calculated. RPR and CRPR values of each state werecompared using a paired t-test, and the relationship between retinal ARPR and corneal ARPR was analyzedby a Pearson correlation test. Results: Parts of the nasal (5° to 25°) and the temporal (5° to 20°) RPR werehyperopic when wearing monofocal soft contact lenses. While wearing multifocal soft contact lenses, eachRPR was more myopic (P<0.001) except 5° nasal and 30° temporal. When wearing multifocal soft contactlenses, parts of the nasal (25° to 30°) and temporal (10° to 30°) CRPR showed greater positive refractivepower than under the monofocal soft contact lenses condition (P<0.001). Retinal ARPR was positivelycorrelated with the corresponding corneal ARPR (r=0.54, P=0.031) while wearing multifocal soft contactlenses. Conclusions: Multifocal soft contact lenses increase the corneal peripheral positive refractive power,thus increasing the retinal peripheral myopic defocus. Clinically, while wearing multifocal soft contactlenses, the change in corneal refractive power can reflect the change in retinal defocus to some extent.
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