Abstract：Objective: To explore the relationship between the difference of accommodation between two eyes and the degree of anisometropia in patients with myopic anisometropia. Methods: In this cross-sectional study, a total of 123 myopic patients (246 eyes) who were admitted to the Qingdao Eye Hospital of Shandong First Medical University aged from 8 to 21 years old were collected from November 2019 to June 2021. According to the difference of equivalent spherical refraction (SE) between two eyes, there were 29 cases in ametropia group (SE difference ≤ 0.25 D), 62 cases in low anisometropia group (1.00 D ≤ SE<2.50 D) and 32 cases in high anisometropia group (SE difference ≥ 2.50 D). All patients meet the binocular best corrected visual acuity (BCVA) ≥ 0.8 and the original data were perfect. The monocular and binocular negative relative accommodation (NRA), accommodative reaction (AR), positive relative accommodation (PRA), accommodative facility (AF) and monocular accommodative amplitude (AMP) were measured by comprehensive optometry. The refraction between the two eyes was determined after optometry under cycloplegic. The differences of interocular accommodation related parameters and the difference of binocular accommodation parameters among the three groups (binocular accommodation parameter difference=myopia diopter higher eye accommodation value-myopia diopter lower eye accommodation value) were analyzed. One-way ANOVA was used to compare the accommodation parameters among the three groups, and Spearman correlation analysis was used to analyze the relationship between the degree of anisometropia and interocular accommodation parameters and the difference between binocular accommodation parameters. Results: There was no statistically significant difference between the three groups in the difference between the NRA, PRA, AR, AF values and the difference between the interocular NRA and AF values (all P>0.05). AR values were -0.03±0.25 in the ametropia group, 0.20±0.30 in the low anisometropia, and 0.26±0.36 in the high anisometropia groups respectively, with statistically significant differences (F=7.36, P<0.001). The PRA difference between the three groups was 0.04±0.27, 0.34±0.72, 0.66±0.63, with statistically significant differences (F=7.47, P<0.001). The difference in AMP was statistically significant (F=9.25, P<0.001) among the three groups (0.41±0.86, -1.07±1.53, and -1.02±2.18, respectively). Multiple comparison showed that there were significant differences in AR difference, PRA difference and AMP difference between anisometropia group and low anisometropia group and high anisometropia group (all P<0.05). In addition, SE differences were associated with lower intensity of AR and AMP differences (r=0.22, P=0.014; r=0.36, P<0.001). Conclusion: The value of accommodation parameters between the eyes of patients with different degrees of myopia refractive variance is different, and there is a correlation of the difference between the difference of AR and AMP with the degree of myopia refractive variance between the eyes.
岳鹏程,杜秋萱,孔玲,等. 不同程度近视性屈光参差患者双眼间调节参数的差异性分析[J]. 中华眼视光学与视觉科学杂志, 2022, 24(12): 933-937.
Pengcheng Yue, Qiuxuan Du, Ling Kong,et al. Analysis on the Difference of Binocular Adjustment Parameters in Patients with Different Degrees of Myopic Anisometropia. Chinese Journal of Optometry Ophthalmology and Visual science, 2022, 24(12): 933-937. DOI: 10.3760/cma.j.cn115909-20220316-00096
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