Abstract:Objective: To determine the clinical features, therapeutic effects, and risk factors of central retinal artery occlusions (CRAO) in young and middle-aged adults. Methods: This was a retrospective study conducted at Jinan Mingshui Eye Hospital from November 2019 to January 2022. Clinical data of 17 (17 eyes) young and middle-aged adults (≤50 years) with CRAO were collected, including general data, medical history, clinical examination results, therapeutic effects, and risk factors. Results: The mean age of the subjects was 43.3±7.0 years (ranging 30-50 years), with 12 males and 5 females.All patients presented with acute vision loss 3 hours to 3 days, and the average blood pressure at the time of visit was 153.24±25.49 / 95.59±15.19 mmHg (1 mmHg=0.133 kPa). Eight eyes had serious visual impairments, including 1 eye with light perception, 5 eyes with hand moving, and 2 eyes with fnger counting. The visual acuity of 5 eyes was worse than 0.1, while 4 eyes were better than 0.15. All patients underwent fundus photography and OCT examination, and 8 patients had Fundus fuorescene angiography examination.All patients had non-arteritic CRAO, including 11 complete CRAO, 5 incomplete CRAO, and 1 case of CRAO with cilioretinal artery sparing. After treatments (follow-up: 5 days to 1 month), visual acuity improved in 10 eyes, 6 eyes had no obvious changes, and 1 eye had worse visual acuity. Blood pressure was elevated in 13 patient (76.5%). Conclusions: Hypertension is the most common system risk factor in the young and middle-aged adults with CRAO. Most patients suffered from serious visual impairments, and the outcomes of visual function were better in incomplete CRAO patients than in complete CRAO patients.
于广委, 陈鑫, 王婷, 等. 中青年视网膜中央动脉阻塞患者的临床观察[J]. 中华眼视光学与视觉科学杂志, 2023, 25(7): 524-529.
GuangweiYu, Xin Chen, Ting Wang, et al. Clinical Observation of Central Retinal Artery Occlusions in the Young and Middle-AgedAdults. Chinese Journal of Optometry Ophthalmology and Visual science, 2023, 25(7): 524-529. DOI: 10.3760/cma.j.cn115909-20221128-00465