Objective To assess the differences and agreements among measurements of cataractous eyes using Lenstar LS900 biometer， Pentacam rotating Scheimpflug photography and a Sirius Scheimpflug-Placido disc topographer. The following measurements were taken： central corneal thickness （CCT）， anterior chamber depth from the corneal endothelium to the anterior lens capsule （ACDendo）， anterior chamber depth from the corneal epithelium to the anterior lens capsule （ACDepi） and mean keratometry （Km）. Methods In this prospective clinical study， CCT， ACD （including ACDendo and ACDepi） and the Km of 40 eyes were randomly obtained by Lenstar， Pentacam and Sirius. All measurements included the 3 methods which were compared using a repeated-measures analysis of variance （ANOVA）， with a Bonferroni multiple comparison correction. Bland-Altman analyses were used to evaluate the agreement between the devices. Results The mean CCTs obtained by Lenstar， Pentacam and Sirius were 528.18±29.12 μm， 533.21±27.02 μm and 534.48±26.15 μm， respectively. The mean ACDendo obtained by Lenstar， Pentacam and Sirius were 2.54±0.41 mm， 2.54±0.43 mm and 2.57±0.43 mm， respectively. The mean ACDepi obtained by Lenstar， Pentacam and Sirius were 3.07±0.41 mm， 3.08±0.42 mm and 3.10±0.43 mm， respectively. The mean Km obtained by Lenstar， Pentacam and Sirius were 44.05±1.69 D， 43.99±1.65 D and 43.93±1.63 D， respectively. There were significant differences among the results of these three methods in CCT （F=11.641， P<0.01）， ACDendo （F=9.961， P<0.01）， ACDepi （F=12.539， P<0.01）， and Km （F=4.186， P<0.05）. The Bland-Altman plot analyses showed that the three devices had comparable results for CCT， ACD and Km. For the maximum absolute values of 95% limits of agreement （LoA） were 26.41 µm， 0.12 mm， 0.12 mm and 0.61 D respectively. Conclusion Lenstar， Pentacam and Sirius demonstrated high agreement for CCT， ACD and corneal curvature measurements in cataractous eyes.
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