Objective To assess the clinical effectiveness of photorefractive keratectomy (PRK)versus laser subepithelial keratectomy (LASEK) for the correction of myopia.Methods A meta-analysis of the literature was conducted that included a review of randomly controlled trials in Pubmed,EMbase,National Knowledge Infrastructure and CQVIP.Data were selected by two independent reviewers using an extraction method.The results included efficacy outcomes (UCVA≥0.8,UCVA≥ 1.0postoperatively),accuracy outcomes (proportion of eyes within ±0.50 diopters of the target refraction postoperatively),safety outcomes (loss of ≥2 lines of BSCVA postoperatively),mean pain scores on day 1 postoperatively,timeline for complete healing of epithelial defects and mean corneal haze scores postoperatively.The Cochrane Collaboration's RevMan 5.0 software was used for statistical analysis.Results Nine RCTs involving 884 eyes with myopia were included.Meta-analysis showed that the efficacy (OR=1.08,95％CI:0.62-1.89),accuracy (OR=0.81,95％CI:0.53-1.24) and safety outcomes between PRK and LASEK were comparable.Compared to PRK,LASEK was better in reducing postoperative corneal haze intensity (WMD=0.23,95％CI:0.13-0.33).Conclusion PRK and LASEK have the same effectiveness,accuracy and safety for myopia,but LASEK results in less corneal haze intensity than PRK postoperatively.