Objective To comprehensively analyze the clinical efficacy of wavefront guided epipolis LASIK (Epi-LASIK) combined with iris recognition. Methods In a prospective study of wavefront guided Epi-LASIK combined with iris recognition, 37 patients (73 eyes) with myopia underwent treatment. The patients were divided into a low-to-moderate myopia group (SE<-6.00 D, 30 eyes) and a high myopia group (SE≥-6.00 D, 43 eyes). All patients were required to undergo preoperative and postoperative examinations that included UCVA, BCVA, refractive status, intraocular pressure, anterior segment slit lamp examinations, corneal topographic tests, WaveScan aberrometer tests, contrast sensitivity (CS) tests, etc. Patients were evaluated at 1 day, 1 week, and 1 month, 3 months and 6 months postoperatively. A t test, ANOVA and chi-square test were used to compare results. Results ?譹?訛Postoperative UCVA: Low-to-moderate myopia patients improved and recovered UCVA faster and better than high myopia patients. At 6 months postoperatively, UCVA in low-to-moderate myopia patients was 5.05±0.11 and was 5.01±0.11 in high myopia patients. There was no significant difference between the groups (t=1.69, P>0.05). ?譺?訛Refraction accuracy: refraction in all patients stabilized within 6 months postoperatively. At 6 months postoperatively, refraction in low-to-moderate myopia patients was +0.16±0.43 D and was -0.21±0.64 D in high myopia patients. ?譻?訛The height of the corneal posterior surface: there was a noticeable drop in height after refractive surgery and the surface remained stable postoperatively in all patients. There was no significant difference between the 2 groups. ?譼?訛Higher order aberrations (HOA): there was an increase in total HOA, coma and spherical aberration in all patients postoperatively. Only trefoil conversely decreased. High myopia patients developed more aberrations than low-to-moderate myopia patients. ?譽?訛CS: the vast majority of patients had a gradual increase in CS and glare sensitivity (GS) postoperatively, reaching a peak at 3 months. Preoperative comparisons showed that CS and GS did not significantly drop in any patients postoperatively. Low-to-moderate myopia patients had better CS and GS for each spatial frequency than high myopia patients. ?譾?訛No patient had serious postoperative complications. Conclusion Wavefront-guided Epi-LASIK combined with iris recognition is more accurate, predictable and stable and results in better visual quality. Clinical efficacy is better for low-to-moderate myopia patients than for high myopia patients.
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