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The use of optical coherence tomography in the analysis of changes in pregnancy-induced hypertension syndrome retinopathy |
Wang Zhixue,Liang Yong,Li Wenying,Wang Xueyan,Zhang Min |
Department of Ophthalmology, Cangzhou Central Hospital, Cangzhou 061001, China |
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Abstract Objective To analyze the changes in pregnancy-induced hypertension syndrome (PIHS) using optical coherence tomography (OCT). Methods A prospective study was conducted to investigate 132 patients (264 eyes) with PHIS who consented to eye examinations that included visual acuity, refraction, slit lamp examination, fundus examination, and OCT. Chi-square tests and Spearman correlation analysis were used to investigate the statistical correlation between retinal detachment seen in OCT exams and patients′ general information (blood pressure, edema, proteinuria). Results ①A fundus examination showed that 232 eyes (87.9%) with PHIS had fundus lesions, including stage I in 16 eyes (6.9%), stage II in 31 eyes (13.4%), and stage Ⅲ in 185 eyes (79.7%). ②OCT examination showed that 172 eyes (65.2%) had abnormalities, including neurosensory serous retinal detachment in 94 eyes (54.6%), pigment epithelium and IS/OS layer changes in 40 eyes (23.3%), and optic disc edema, retinal hemorrhage and other changes in 38 eyes (22.1%). ③Since hypertension, edema, and proteinuria are risk factors for retinal detachment, a higher blood pressure leads to more severe proteinuria and edema, which are correlated with a higher risk of retinal detachment (r=0.156, 0.208, 0.296, P<0.05). Conclusion As a non-contact, non-invasive tomographic imaging technique for severe PIHS, OCT provides objective and accurate inspection images that detect changes in the fundus.
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Corresponding Authors:
Wang Zhixue, Email: wangzhixue5@163.com
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