Objective: To introduce the surgical technique of big-bubble combined with the wet-peeling technique for deep anterior lamellar keratoplasty. Methods: Form January 2016 to June 2017, 59 Herpes simplex keratitis (HSK) patients at Eye Hospital, Wenzhou Medical University underwent deep anterior lamellar keratoplasty. When performing big-bubble deep anterior lamellar keratoplasty for treatment of herpetic corneal scars, we switched to the wet-peeling technique to finish the surgery if we encountered a type-2 big bubble or small bubbles. Results: Deep anterior lamellar keratoplasty was successfully performed on all 59 eyes with no occurrence of a microperforation. The occurrence rate of type-2 big bubbles was 71%.Conclusions: Type-2 big bubbles occurred in a high proportion of HSK patients. Converting to the wet-peeling technique for type-2 big bubbles or small bubbles, maintained the pre-Descemet's membrane and was a safe procedure.