静坐和运动时间与视网膜血管管径的相关性

doi:10.3760/cma.j.issn.1674-845X.2017.11.003

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Abstract

Objective: To explore the association between sedentary behavior, physical activity and retinal microvessels caliber in normal people. Methods: In this cross-sectional study, 6 560 participants, age ≥ 40 years (range40 – 87 years) were recruited from March 2008 to July 2017. The calibers of retinal microvessels were graded using retinal photography, and each participant's self-reported sedentary behavior and physical activity time were obtained through an extensive questionnaire. Physical activity was classified as high-intensity activity(running, swimming and basketball), moderate-intensity activity (Taichi, shuttlecock kicking and cycling)and low intensity activity (walking). Multivariate linear regression was used to explore the relationship between life activity habits and retinal microvessel caliber. Results: After exclusion of some recruited particpants for different reasons, 5 857 subjects were inclinded in the final analysis. After adjustment for age, gender,body mass index, blood pressure, fasting plasma glucose, triglycerides, total cholesterol, smoking status,and drinking status, the sedentary time was negatively associated with the caliber of the central retinal arterioles (β=-0.29, P =0.032). There was no significant association between physical activity and retinal vascular caliber. Conclusions: Sedentary time was significantly and independently associated with a decrease in the caliber of central retinal arterioles. The results suggest that sedentary behavior probably increases the risk of cardiovascular diseases among Chinese adults.

Key words： sedentary behavior physical activity life style retinal microvessels caliber

Received: 21 July 2017

Fund:

This study was funded by Science and Technology Planning Project of Guangdong Province(2013B20400003); Fundamental Research Funds of the State Key Laboratory of Ophthalmology State Key Laboratory of Ophthalmology (3030901010058)

Corresponding Authors: Mingguang He, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China (Email: mingguang_he@yahoo.com)

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	Xueping Zhang
	Chimei Liao
	Wei Zhang
	Hongfei Huang
	Mingguang He

Cite this article:

Xueping Zhang,Chimei Liao,Wei Zhang等. Effects of sedentary behavior and physical activity on the caliber of retinal microvessels in Chinese adults[J]. Chinese Journal of Optometry Ophthalmology and Visual science, 2017, 19(11): 650-655.

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https://www.cjoovs.com/EN/10.3760/cma.j.issn.1674-845X.2017.11.003 OR https://www.cjoovs.com/EN/Y2017/V19/I11/650

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