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Distribution Characteristics and Related Factors of Macular Thickness in Children and Teenagers with Normal Eyes |
Siqi Wu, Yishuang Xiao |
Department of Ophthalmology, Kunming Children's Hospital, Kunming 650034, China |
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Abstract Objective: To investigate the distribution characteristics and related factors of macular thickness in children and teenagers with healthy eyes. Methods: This descriptive study included 284 children and teenagers (568 normal eyes) with a mean age of 10.1±2.8 years, range 4-17 years, and a refractive diopter range of -8- +6 D who were seen at the Department of Ophthalmology, Kunming Children's Hospital from July 2014 to August 2016. Macular thickness was measured by optical coherence tomography (OCT), 6 mm diameters that included 9 areas (A1-A9). Eyes were divided into different groups based on sex,left and right eyes, age (≤10 years and >10 years, two groups), and spherical equivalent (myopia: SE≤ -0.50 D; emmetropia: -0.50 D10 years of age groups except for zones A1 of the left eyes and A1, A2 of the right eyes (t=3.322, P=0.001; t=3.240, P=0.001; t=2.274, P=0.024). In the comparison of different dioptric groups, the hyperopia group had the thickest macula and the myopia group had the thinnest except for zones A6, A8, A9. There was no statistically significant difference in other zones between the three groups. Conclusions: The thickness mapping of the macula demonstrates that macular thickness is not evenly distributed across the 6 mm diameters. The macular averages at the central zone (diameter: 1.0 mm) are the thinnest and the thickest are at the paracentral zone (diameter: 1.0-3.0 mm). No correlations were found between macular thickness and age or sex. The central zone macular thickness tends to thin with age. The macula is thickest in the hyperopia group and is thinnest in the myopia group in the superior, inferior, and temporal areas of the peripheral zones.
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Received: 30 May 2019
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Fund:Kunming Health and Family Planning Commission, Diagnosis and Treatment Center Program of Kunming Children's Eyes [2016-SW(T)-18] |
Corresponding Authors:
Yishuang Xiao, Department of Ophthalmology, Kunming Children's Hospital, Kunming 650034, China (Email: 603504269@qq.com)
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