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| Comparative Observation on Improving Eyeshade Covering Compliance after Atropine was Applied to Healthy Eyes |
| Huade Wang, Xiaona Pei, Lan Shen, Lin Wei |
| Puyang Eye Hospital (Second People's Hospital of Puyang City), Puyang 457000, China |
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Abstract Objective: To observe whether healthy eye treated with atropine can improve children's compliance with eye occlusion. Methods: This was a prospective study. From February 2015 to February 2017, 136 eyes of 136 amblyopic children aged 7 to 9 years who were treated in Puyang Eye Hospital and were prescribed glasses for the first time, with a corrected vision of ≤0.3 in amblyopia, and whose age met the criteria for cover therapy were selected. The data from three months, six months and one year after treatment were statistically analyzed. During the observation period, the patients were divided into two groups based on the occlusion treatment method: the observation group (group A, 68 cases) was covered with an eyepatch for not less than 6 hours per day on the basis of atropine's healthy eyes on Mondays and Wednesdays. The control group (group B, 68 cases) was simply covered with an eye patch for not less than 6 hours per day. Parents and teachers were asked to closely observe the removal and wearing of the blindfolds and compare the compliance and improvement of visual acuity of the two groups after three months, six months and one year. Chi-square test and independent t test were used. Results: The treatment compliances of group A (94%, 87%, 78%) and group B (75%, 65%, 57%) were significantly different (χ2 =9.517, P=0.002; χ2 =9.003, P=0.002; χ2 =6.585, P=0.010). The effective treatment rate for group A (44%, 63%, 76%) was significantly different from group B (28%, 12%, 59%)(χ2 =3.860, P=0.049; χ2 =5.785, P=0.016; χ2 =4.838, P=0.028). The corrected visual acuity of amblyopia in group A was better than that in group B 3, 6, 12 months after treatment (t=-2.355, P=0.011; t=-3.619, P=0.002; t=-4.922, P<0.001). One year later, the total cure rates for group A and group B were 56% and 38%, which were statistically significant (χ2 =4.250, P=0.039). The actual cure rates were 72% and 67% which were not statistically significant (χ2 =0.269, P=0.604). Conclusions: For amblyopia patients who need occlusiontherapy, atropine can significantly improve compliance and the effectivityrate, and the total cure rate is significantly better than that of simple occlusion.
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Received: 23 April 2019
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Corresponding Authors:
Huade Wang, Puyang Eye Hospital (Second People's Hospital of Puyang City), Puyang 457000, China (Email: 2236362771@qq.com)
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