穿透性角膜移植术与板层角膜移植术治疗圆锥角膜术后客观视觉质量比较

doi:10.3760/cma.j.cn115909-20200430-00190

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Abstract Objective: To evaluate the optical quality of keratoconus patients after penetrating keratoplasty (PKP) or lamellar keratoplasty (LKP) using a dual-channel optical quality analysis system (OQAS). Methods: This was a prospective study. A total of 40 keratoconus patients in Qingdao Eye Hospital were involved in this study from January 2016 to December 2017. And they were divided into a PKP group (23 patients, 24 eyes) or LKP group (17 patients, 19 eyes), depending on the surgical selection. Visual acuity, astigmatism, the density of the corneal endothelium cells, objective scatter index (OSI), predicted visual acuity (PVA), modulation transfer function cut-off frequency (MTF cutoff), Strehl ratio (SR) and tear film analysis of the mean OSI with a dual-channel optical quality analysis system were compared. Data were analyzed using χ2 test and independent t test. Results: There was no statistically significant difference between the PKP group and the LKP group for best corrected visual acuity, and spherical and cylindrical powers. But there was a significant difference between the two groups in the density of the corneal endothelium cells (t=3.91, P<0.001). In addition, there were statistically significant differences between the PKP and the LKP groups for the MTF cutoff and PVA100 (t=2.58, P=0.01; t=2.66, P=0.01). There was also a statistically significant difference between the PKP group and the LKP group in the tear film analysis mean OSI (t=3.48, P<0.001). Conclusions: The objective optical qualities of keratoconus patients after PKP measured by OQAS are better than after LKP, and the MTF cutoff and contrast vision are also better.

Key words： keratoconus penetrating keratoplasty lamellar keratoplasty objective visual quality

Received: 30 April 2020

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Fund: Natural Science Foundation of Shandong Province (ZR2015YL026); Qingdao Southern District Science and Technology Development Fund Project (2018-4-030-YY)

Corresponding Authors: Ting Liu, Qingdao Eye Hospital of Shandong First Medical University, Qingdao 266071, China; State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong First Medical University & Shandong Academy of Medical Sciences, Qingdao 266071, China (Email: liuting213@163.com)

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https://www.cjoovs.com/EN/10.3760/cma.j.cn115909-20200430-00190 OR https://www.cjoovs.com/EN/Y2020/V22/I11/836

[1]	史伟云, 高华, 李莹. 努力规范我国圆锥角膜的临床诊疗工作. 中华眼科杂志, 2019, 55(6): 401-404. DOI: 10.3760/cma.j.issn. 0412-4081.2019.06.001.
[2]	Xu CC, Xue T, Wang QM, et al. Repeatability and reproducibility of a double-pass optical quality analysis device. PLoS One, 2015, 10(2): e0117587. DOI: 10.1371/journal.pone.0117587.
[3]	乔利亚, 蔡啸谷, 万修华, 等. 应用双通道客观视觉质量分析系统与光线追踪波阵面像差系统分析正常人眼调制传递函数. 中华眼科杂志, 2015, 51(1): 20-25. DOI: 10.3760/cma. j.issn.0412-4081.2015.01.006.
[4]	谢立信. 角膜移植学. 人民卫生出版社, 2000: 11.
[5]	Naderan M, Shoar S, Rezagholizadeh F, et al. Characteristics and associations of keratoconus patients. Cont Lens Anterior Eye, 2015, 38(3): 199-205. DOI: 10.1016/j.clae.2015.01.008.
[6]	肖显文. 双通道视觉质量分析系统在眼科的应. 国际眼科纵览, 2013, 37(2): 77-82.
[7]	Ren Z, Xu L, Fan Q, et al. Assessment of visual quality in eyes with forme fruste keratoconus and mild and moderate keratoconus based on optical quality analysis system II parameters. J Ophthalmol, 2020, 2020: 7505016. DOI: 10.1155/2020/7505016.
[8]	俞阿勇, 施恩, 王勤美, 等. 不同年龄段成年人眼的综合光学质量客观评估. 中华眼科杂志, 2016, 52(1): 47-50. DOI: 10.3760/cma.j.issn.0412-4081.2016.01.012.
[9]	Tian M, Miao H, Shen Y, et al. Intra- and intersession repeatability of an optical quality and intraocular scattering measurement system in children. PLoS One, 2015, 10(11): e0142189. DOI: 10.1371/journal.pone.0142189.
[10]	张佳, 陈雍, 赵文雯, 等. 基于双通道技术的视觉质量分析系统在评估轻度圆锥角膜视觉质量中的应用. 中华眼视光学与视觉科学杂志, 2019, 21(12): 900-905. DOI: 10.3760/cma. j.issn.1674-845X.2019.12.004.
[11]	Leonard AP, Gardner SD, Rocha KM, et al. Double-pass retina point imaging for the evaluation of optical light scatter, retinal image quality, and staging of keratoconus. J Refract Surg, 2016, 32(11): 760-765. DOI: 10.3928/1081597X-20160728-02.
[12]	Ye C, Ng PK, Jhanji V. Optical quality assessment in normal and forme fruste keratoconus eyes with a double-pass system: a comparison and variability study. British Journal of Ophthalmology, 2014, 98: 1478-1483.
[13]	李姗姗, 高华, 李素霞, 等. 圆锥角膜行光学板层角膜移植术后早期缝线松动的影响因素. 中华眼视光学与视觉科学杂志, 2011, 13(2): 131-135. DOI: 10.3760/cma.j.issn.1674- 845X.2011.02.012.
[14]	胥晓涵, 刘丽梅, 史伟云, 等. 圆锥角膜行板层角膜移植术和穿透性角膜移植术后屈光状态的比较. 临床眼科杂志, 2013, 21(1): 5-8. DOI: 10.3969/j.issn.1006-8422.2013.01.002.
[15]	施节亮, 冯一帆, 郁继国, 等. 深板层角膜移植术与穿透角膜移植术治疗圆锥角膜临床疗效的Meta分析. 中华实验眼科杂志, 2012, 30(10): 926-931. DOI: 10.3760/cma.j.issn.2095- 0160.2012.10.017.
[16]	Kobashi H, Kamiya K, Shimizu K. Impact of forward and backward scattering and corneal higher-order aberrations on visual acuity after penetrating keratoplasty. Semin Ophthalmol, 2018, 33(6): 748-756. DOI: 10.1080/08820538.2018.1427767.
[17]	Kamiya K, Asato H, Shimizu K, et al. Effect of intraocular forward scattering and corneal higher-order aberrations on visual acuity after Descemet's stripping automated endothelial keratoplasty. PLoS One, 2015, 10(6): e0131110. DOI: 10.1371/ journal.pone.0131110.
[18]	陆勤康, 童奇湖, 赖晓明, 等. 深板层角膜移植术与穿透性角膜移植术治疗真菌性角膜溃疡的效果比较. 中华眼视光学与视觉科学杂志, 2011, 13(3): 231-233. DOI: 10.3760/cma.j.issn. 1674-845x.2011.03.017.
[19]	徐建江, 乐琦骅, 孙兴怀, 等. 深板层角膜移植术与穿透性角膜移植术治疗圆锥角膜的临床分析. 中华眼科杂志, 2007, 43(7): 583-588. DOI: 10.3760/j.issn.0412-4081.2007.07.003.
[20]	秦勤, 陈晖, 李一壮, 等. TICL植入术在矫治圆锥角膜深板层角膜移植术后屈光不正中的临床应用. 中华实验眼科杂志, 2016, 34(2): 137-142. DOI: 10.3760/cma.j.issn.2095- 0160.2016.02.009.
[21]	孙龙格, 马忠旭, 马林, 等. 基于OQAS-Ⅱ视觉质量参数对轻中度干眼泪膜稳定性动态变化的评估. 中华实验眼科杂志, 2017, 35(4): 344-348. DOI: 10.3760/cma.j.issn.2095- 0160.2017.04.012.
[22]	余利华, 姜珺, 毛欣杰, 等. 圆锥角膜患者配戴RGPCL前后视觉相关生活质量的比较. 中华眼视光学与视觉科学杂志, 2018, 20(3): 145-149. DOI: 10.3760/cma.j.issn.1674-845X. 2018.03.004.