新疆塔城地区汉族和哈萨克族人群翼状胬肉患病率及危险因素研究

doi:10.3760/cma.j.cn115909-20210330-00125

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Abstract

Objective: To investigate the prevalence and risk factors of pterygium in Han and Kazak ethnic groups

aged 50 and older in the Tacheng region of Xinjiang. Methods: This was a cross-sectional study. The

prevalence of pterygium in people aged 50 years and older in the Tacheng region was investigated and

studied by the Jiu Shi Hospital of Xinjiang Production and Construction Corps from October 2015 to June

2018. The basic sampling units (BSU) were divided by administrative area, with approximately 1 000

people in each BSU, or divided into more than 2 BSUs if the BSU exceeded 1 500 people. The Tacheng

region was divided into 240 BSUs. We randomly selected 12 BSUs by using random number table method.

Questionnaires were used to collect information such as age, ethnicity, gender, hypertension, diabetes,

smoking, age-related cataract, coronary heart disease, duration of UV exposure (summer), and duration of

UV exposure (winter). Pterygium was diagnosed and graded clinically by slit-lamp examination. Rank sum

test was performed to compare the association between the above factors and the prevalence of pterygium.

Then, we entered all significant factors (predefined as P<0.05 in Rank sum test) into a multivariable

logistic regression model to identify independent factors correlating with pterygium. Results: A total of

2 114 individuals were included in this study, of which 489 were diagnosed with pterygium (23.13%),

including 65(21.04%) in group aged 50-59, 168(24.93%) in group aged 60-69, 219(23.08%) in group

aged 70-79, 37(20.33%) in group aged above 80. Rank sum test showed that gender (F=5.560, P=0.018),

smoking (F=6.568, P=0.010), duration of UV exposure (summer) (F=8.884, P<0.001), age-related cataract

(F=4.397, P=0.036), and refractive error (F=8.273, P=0.004) were associated with pterygium. Further

logistic multiple regression analysis revealed that UV exposure (summer) [0-4: OR=2.184, 95%CI: 0.502-

9.175; 4-8: OR=1.651, 95%CI: 1.256-3.295], and refractive error (OR=1.903, 95%CI: 1.425-2.248)

were independent risk factors for the presence of pterygium in this region. Conclusions: The prevalence

of pterygium in people aged 50 years and older in Tacheng, Xinjiang is 23.13%, There is no significant

difference between Han and Kazak ethnic groups. Ultraviolet radiation (summer) is independently

associated with pterygium.

Key words： Pterygium prevalence risk factors Tacheng region Xinjiang

Received: 30 March 2021

PACS:

Fund:Hebei postgraduate demonstration course construction project (KCJSZ2020055)

Corresponding Authors: Ye He, Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin 300384, China (Email: yehe24@outlook.com)

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Cite this article:

Xiao Li,Guoqing Li,Jing Xu等. The Prevalence and Risk Factors of Pterygium in Han and Kazak Ethnic Groups in Tacheng, Xinjiang[J]. Chinese Journal of Optometry Ophthalmology and Visual science, 2021, 23(12): 903-909.

URL:

https://www.cjoovs.com/EN/10.3760/cma.j.cn115909-20210330-00125 OR https://www.cjoovs.com/EN/Y2021/V23/I12/903

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