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| Comparative Study of the Progression of Low to Moderate Myopia in Children 6−12 Years of Age in the Xi'an First Hospital before and after the Outbreak of COVID-19 |
| Pan Li, Tong Li, Jin Wang, Ruoxin Wang, Xuehui Zhang |
Department of Ophthalmology, Xi'an First Hospital, Institute of Ophthalmology, Key Lab of Ophthalmology, Clinical Center for Ophthalmology, Xi'an 710002, China |
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Abstract Objective: To compare the progression of low to moderate myopia in children 6-12 years of age in
the Xi'an First Hospital before and after the COVID-19 epidemic. Methods: This was a retrospective
cohort study. One hundred cases (200 eyes) of children 6-12 years of age with binocular myopia who
were admitted to the Department of Ophthalmology in Xi'an No.1 Hospital before the outbreak of the COVID-19 epidemic (December 2018 to January 2019) and after the outbreak (December 2019 to January
2020) participated in the study. Follow-up records were recorded for 0.5 and 1 year. The mean age of the
pre-epidemic group was 9.6±1.2 years, and the mean age of the post-epidemic group was 9.2±2.4 years.
Changes in the ocular axis (AL), spherical equivalent (SE) and axial/corneal curvature ratio (AL/CR) at
baseline, 0.5 and 1 year were retrospectively analyzed in the 2 groups, and the data were compared by a
paired t test. Results: At the 0.5 year follow-up, the pre-epidemic group showed less AL growth than the
post-epidemic group (0.27±0.16 mm vs. 0.36±0.19 mm) (t=-6.228, P<0.001), an increase in SE (-0.48±
0.37 D vs. -0.74±0.63 D) (t=-2.375, P<0.001), and an increase in AL/CR ratio (0.017±0.028 vs.
0.029±0.031) (t=-6.052, P<0.001). At the 1 year follow-up, the pre-epidemic group showed less AL growth
than the post-epidemic group (0.46±0.31 vs. 0.61±0.24) (t=1.138, P<0.001), an increase in SE (-0.90±
0.41 D vs. -1.25±0.48 D) (t=7.253, P<0.001), and an increase in the AL/CR ratio (0.030±0.051 vs.
0.046±0.036) (t=5.049, P=0.032). Conclusions: After the outbreak of COVID-19, the progression of
myopia in 6-12 year-old school-age children in the post-epidemic is faster than in the pre-epidemic, mainly
manifested in AL, SE and AL/CR
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Received: 19 May 2021
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Corresponding Authors:
Xuehui Zhang, Department of Ophthalmology, Xi'an First Hospital, Institute of Ophthalmology, Key Lab of Ophthalmology, Clinical Center for Ophthalmology, Xi'an 710002, China (Email:1346841463@qq.com)
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