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| Effects of Different Surgical Methods on Dry Eye Symptoms in Patients with Glaucoma Complicated with Cataract |
| Mengmeng Huo1, Xiu Wang2, Xue Gao1, Yunpeng Yang1, Xiaohui Jiang2 |
1Weifang Medical University, Weifang 261053, China
2Department of Ophthalmology, Qingdao Municipal Hospital, Qingdao 266071, China |
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Abstract Objective: To compare the effects on dry eye symptoms from phacoemulsification (phaco) combined
with intraocular lens (IOL) implantation, phaco-IOL-goniosynechialysis and phaco-IOL-trabeculectomy.
Methods: This was a retrospective control study. Ninety-two patients were recruited from June 2019
to June 2020 in the Department of Ophthalmology at Qingdao Municipal Hospital. Group A (40 eyes)
underwent phacoemulsification, group B (38 eyes) underwent phaco-IOL-goniosynechialysis, and group
C (40 eyes) underwent phaco-IOL-trabeculectomy. Noninvasive first tear film break-up time (NIFBUT),
noninvasive average tear film break-up time (NIA-BUT), tear meniscus height (TMH), meibomian
gland loss scores, basal tear secretion, and corneal perception were analyzed and compared at 1 day
preoperatively and 3 days, 1 week, 1 month, and 3 months postoperatively using the Oculus Keratograph
5M, SchirmerⅠ test (SⅠT) and Cochet-Bonnet Asthesiometer. Quantitative data consistent with normal
distribution were analyzed by repeated measures ANOVA. The LSD-t test was used for intra-group
comparison and one-way ANOVA was used for inter-group comparison. Kruskal-Wallis H test was used
to compare the data that did not conform to normal distribution. Results: From postoperative 3 days to 3
months, the NIF-BUT and NIA-BUT of group C dropped more significantly than those of the other two
groups (P<0.05). NIF-BUT and NIA-BUT both returned to preoperative levels at 1 month after surgery in
groups A and B. TMH and SⅠT in group C increased at 3 days and 1 week postoperatively (P<0.05), and
returned to preoperative levels at 1 month postoperatively. At each time point postoperatively, TMH and
SⅠT of groups A and B were not significantly different compared to baseline. At 3 months postoperatively,
meibomian gland loss scores increased significantly, and there was a statistically significant difference in
group C (t=-9.48, P<0.001). At each time point postoperatively, meibomian gland loss scores were not
significantly different compared to baseline between groups A and B. The corneal perception of each group
receded and the perception in group C was more serious and different than the other two groups from 3
days to 1 month postoperatively (P<0.05). At 3 months postoperatively, corneal perception in group C
returned to the preoperative level and there was no statistically significant difference. It was restored to the
preoperative level at 1 month postoperatively and there was no statistically significant difference between
group A and B. Conclusions: Phaco-IOL-trabeculectomy has a great influence on SⅠT and corneal
perception. Corneal perception recovered at 3 months postoperatively, but tear film stability and meibomian
gland loss was still lost.
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Received: 10 August 2021
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Corresponding Authors:
Xiaohui Jiang, Department of Ophthalmology, Qingdao Municipal Hospital,Qingdao 266071, China (Email: ocularjxh@163.com)
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