|
|
The Application of Pentacam Anterior Segment Analyzer in the Selection of Initial Sagittal Height in Scleral Lens Fitting |
Shanshan Xu1, Yan Hu1, Yan Qi1, Wei Chen2, Jinsong Xue1 |
1Nanjing Medical University Affiliated Eye Hospital, Nanjing 210029, China
2Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China |
|
|
Guide |
|
Abstract Objective: To evaluate the value of using the Pentacam anterior segment analyzer to measure ocular
anterior segment parameters in the selection of initial lens sagittal depth (LSD) for scleral lenses (SL).
Methods: Retrospective serial case study. Thirty-two patients (53 eyes) with irregular corneal astigmatism
or dry eye disease were enrolled and fitted with SL in the Affiliated Eye Hospital of Nanjing Medical
University from October 2020 to June 2021. All patients underwent general ophthalmic examinations
before the initial SL fitting evaluation. Pentacam was used to obtain the ocular anterior segment parameters,
such as flat keratometry (Kf), steep keratometry (Ks), corneal astigmatism, aspheric factor (Q-value),
central corneal thickness (CCT), corneal diameter, and anterior chamber depth (ACD). In addition, the
built-in caliper of the Pentacam was used to measure corneal sagittal height (CSH) at a 13.50 mm chord
length. A Pearson or Spearman correlation analysis was used to evaluate the relationship between the
modified LSD and above-mentioned parameters measured by Pentacam, and a linear regression model
was created. Results: All patients completed the first SL fitting evaluation.The CSH measured in the
Scheimpflug images of the Pentacam were 3 746±187 μm under a 13.50 mm chord length, and the modified
LSD was 3 622±206 μm after fitting. The results of a correlation analysis showed that the modified LSD
was positively associated with Kf, Ks, corneal astigmatism, ACD and CSH (r ranged from 0.36 to 0.84, all
P<0.05). The modified LSD was negatively correlated with CCT (r=-0.35, P=0.011). However,there was
no correlation between the Q-value or corneal diameter and the modified LSD. Defining the modified LSD
as a dependent variable, the linear regression model showed that CSH measured by Pentacam was highly
correlated with the modified LSD after correcting for the other covariates. The linear regression equation
is LSD=416.996+0.854×CSH (adjusted R2=0.63, F=89.17, P<0.001). Conclusions: Some ocular anterior
segment parameters measured by Pentacamare correlated with the modified LSD, and CSH can be used as
an important reference for the selection of LSD inthe process of SL fitting.
|
Received: 13 September 2021
|
|
Fund: |
Corresponding Authors:
Jinsong Xue, Nanjing Medical University Affiliated Eye Hospital, Nanjing 210029,China (Email: 25068411@qq.com)
|
|
|
|
[1] |
Michaud L, Lipson M, Kramer E, et al. The official guide to scleral lens terminology. Cont Lens Anterior Eye, 2020, 43(6):
|
52 |
9-534. DOI: 10.1016/j.clae.2019.09.006.
|
[2] |
Fadel D, Ezekiel DF. Fenestrated scleral lenses: back to the origins? review of their benefits and fitting techniques.Optom Vis Sci, 2020, 97(9): 807-820. DOI: 10.1097/OPX.0000000000001562.
|
[3] |
La Porta WS, Becco D SR, Gomes J, et al. The use of the esclera scleral contact lens in the treatment of moderate to severe dry
|
|
eye disease. Am J Ophthalmol, 2016, 163: 167-173. e1. DOI:10.1016/j.ajo.2015.11.034.
|
[4] |
Scanzera AC, Ahmad A, Shorter E. Adjunct use of therapeutic scleral lens for exposure keratopathy after severe chemical burn. Case Rep Ophthalmol, 2021, 12(1): 243-247. DOI: 10.1159/000511223.
|
[5] |
Kumar M, Shetty R, Lalgudi VG, et al. The effect of scleral lenses on vision, refraction and aberrations in post-LASIK ectasia, keratoconus and pellucid marginal degeneration.Ophthalmic Physiol Opt, 2021, 41(4): 664-672. DOI: 10.1111/opo.12802.
|
[6] |
Sorbara L, Maram J, Fonn D, et al. Metrics of the normal cornea: anterior segment imaging with the Visante OCT. Clin Exp Optom, 2010, 93(3): 150-156. DOI: 10.1111/j.1444-0938.2010.00472.x.
|
[7] |
Vincent SJ, Alonso-Caneiro D, Collins MJ. Optical coherence tomography and scleral contact lenses: clinical and research applications. Clin Exp Optom, 2019, 102(3): 224-241. DOI: 10.1111/cxo.12814.
|
[8] |
Tom LM, Jacobs DS. Advances in anterior segment OCT for the design and fit of scleral lenses. Int Ophthalmol Clin, 2019,59(4): 31-40. DOI: 10.1097/IIO.0000000000000284.
|
[9] |
Doctor K, Vunnava KP, Shroff R, et al. Simplifying and understanding various topographic indices for keratoconus using Scheimpflug based topographers. Indian J Ophthalmol, 2020,68(12): 2732-2743. DOI: 10.4103/ijo.IJO_2111_20.
|
[10] |
Phu J, Tong J, Kalloniatis M. Intra-session repeatability of anterior chamber depth across the chamber width using Pentacam Scheimpflug imaging in healthy subjects. Ophthalmic Physiol Opt, 2021, 41(6): 1273-1284. DOI: 10.1111/opo.12880.
|
[11] |
Ye Y, Zhao J, Niu L, et al. Long-term evaluation of anterior lens density after implantable collamer lens V4c implantation in
|
|
patients with myopia over 40 years old. Br J Ophthalmol, 2021:1-6. DOI: 10.1136/bjophthalmol-2021-319205.
|
[12] |
Rathi VM, Mandathara PS, Dumpati S, et al. Change in vault during scleral lens trials assessed with anterior segment optical
|
|
coherence tomography. Cont Lens Anterior Eye, 2017, 40(3):157-161. DOI: 10.1016/j.clae.2017.03.008.
|
[13] |
Pullum KW. Contact lenses. Oxford: Butterworth Heinemann,1997: 566-608.
|
[14] |
van der Worp E, Bornman D, Ferreira DL, et al. Modern scleral contact lenses: a review. Cont Lens Anterior Eye, 2014, 37(4):
|
24 |
0-250. DOI: 10.1016/j.clae.2014.02.002.
|
[15] |
Witsberger E, Schornack M. Scleral Lens Use in Neurotrophic Keratopathy: a review of current concepts and practice. Eye
|
|
Contact Lens, 2021, 47(3): 144-148. DOI: 10.1097/ICL.0000000000000748.
|
[16] |
Otchere H, Jones L, Sorbara L.The impact of scleral contact lens vault on visual acuity and comfort. eye contact lens, 2018,
|
44 |
(Suppl 2): S54-S59. DOI: 10.1097/ICL.0000000000000427.
|
[17] |
Ritzmann M, Caroline PJ, Borret R, et al. An analysis of anterior scleral shape and its role in the design and fitting of scleral
|
|
contact lenses. Cont Lens Anterior Eye, 2018, 41(2): 205-213.DOI: 10.1016/j.clae.2017.10.010.
|
[18] |
曹建雄, 常平骏, 李瑾, 等. 基于Pentacam对角膜屈光指数的评价. 中华眼视光学与视觉科学杂志, 2020, 22(8): 596-601.DOI: 10.3760/cma.j.cn115909-20191205- 00326.
|
[19] |
李鸿钰, 李军, 宋慧. 基于Pentacam的角膜后前表面曲率半径比值分布及其对角膜屈光力的影响. 眼科新进展, 2020,40(11): 1065-1069. DOI: 10.13389 /j.cnki.rao.2020.0238.
|
[20] |
Weber SL, Ambrosio RJ, Lipener C, et al. The use of ocular anatomical measurements using a rotating Scheimpflug camera
|
|
to assist in the Esclera (R) scleral contact lens fitting process.Cont Lens Anterior Eye, 2016, 39(2): 148-153. DOI: 10.1016/j.
|
|
clae.2015.09.007.
|
[21] |
Piñero DP, Martinez-Abad A, Soto-Negro R, et al. Differences in corneo-scleral topographic profile between healthy and keratoconus corneas. Cont Lens Anterior Eye, 2019, 42(1): 75-84. DOI: 10.1016/j.clae.2018.05.005.
|
[22] |
Van Nuffel S, Consejo A, Koppen C, et al. The corneoscleral shape in keratoconus patients with and without specialty lens
|
|
wear. Cont Lens Anterior Eye, 2021, 44(3): 101343. DOI: 10.1016/j.clae.2020.06.001.
|
[23] |
Mas-Aixala E, Gispets J, Lupon N, et al. The variability of corneal and anterior segment parameters in keratoconus. Cont
|
|
Lens Anterior Eye, 2016, 39(6): 466-470. DOI: 10.1016/j.clae.2016.05.003.
|
[24] |
DeNaeyer G, Sanders DR, Michaud L, et al. Correlation of corneal and scleral topography in cases with ectasias and normal
|
|
corneas: the SSG study. J Cont Lens Res Sci, 2019, 3(1): 10-20.DOI: 10.22374/jclrs.v3i1.33.
|
[25] |
Kim S, Lee JS, Park YK, et al. Fitting miniscleral contact lenses in Korean patients with keratoconus. Clin Exp Optom, 2017,100(4): 375-379. DOI: 10.1111/cxo.12424.
|
[26] |
Macedo-De-Araujo RJ, Amorim-De-Sousa A, Queiros A, et al. Relationship of placido corneal topography data with scleral lens fitting parameters. Cont Lens Anterior Eye, 2019, 42(1):20-27. DOI: 10.1016/j.clae.2018.07.005.
|
[27] |
Compan V, Oliveira C, Aguilella-Arzo M, et al. Oxygen diffusion and edema with modern scleral rigid gas permeable contact lenses. Invest Ophthalmol Vis Sci, 2014, 55(10): 6421-6429. DOI: 10.1167/iovs.14-14038.
|
[28] |
Barr JT, Wilson BS, Gordon MO, et al. Estimation of the incidence and factors predictive of corneal scarring in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK)Study. Cornea, 2006, 25(1): 16-25. DOI: 10.1097/01.ico.0000164831.87593.08.
|
|
|
|