弱视儿童与正常儿童对比敏感度差异

doi:10.3760/cma. j.cn115909-20210817-00322

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Abstract Objective: To explore the change in contrast sensitivity (CS) in amblyopic children before and after treatment and compare the difference in CS between amblyopic children and normal children. Methods: This was a retrospective case-control study. Amblyopic children treated in Aier Ophthalmology Hospital Affiliated to Wuhan University during the period from June 2019 to December 2020 were selected as the amblyopia group. And normal children were selected as the control group. Based on the diagnostic criteria for the degree of amblyopia, the amblyopic eyes were divided into three groups: mild, moderate and severe. A total of 83 cases (137 eyes) in the amblyopia group and 26 cases (52 eyes) in the control group were selected. The 54 cases included binocular amblyopia (108 eyes) and 29 cases of unilateral amblyopia (29 amblyopic eyes and 29 fellow eyes). The numbers of mild, moderate, and severe amblyopic eyes were 45, 69, and 23, respectively. The CS of the fellow eyes of unilateral amblyopia and each group of amblyopic eyes were examined before treatment and for one year after treatment. The normal control group was also examined. A paired t test, LSD-t test, and Spearman correlation test were used in statistical analyses. Results: For fellow eyes of unilateral amblyopia and all the amblyopic eyes, all spatial frequencies of CS before treatment were lower than that in the normal group (P<0.05), and CS after treatment was higher than that before treatment in the same group (P<0.05). For a spatial frequency of 18.0 cpd, there were differences between fellow eyes and mild amblyopic eyes after treatment compared to the normal group (P<0.05), but there was no significant difference in other spatial frequencies. In spatial frequencies of 6.0, 12.0 and 18.0 cpd, there were differences between moderate amblyopic eyes after treatment compared to the normal group (P<0.05), but there was no significant difference for 3.0 cpd. For severe amblyopic eyes, there were differences in all spatial frequencies between the treatment group and the normal group (P<0.05). In each spatial frequency before treatment, the CS of amblyopic eyes was negatively correlated with the degree of amblyopia (r=-0.52, -0.60, -0.55, -0.54, P<0.001). Conclusion: The CS of children with different levels of severity for amblyopia is lower than the normal control group. CS will increase to a certain extent after treatment, and it is easier to recover the CS of mild amblyopic eyes than for moderate and severe amblyopic eyes

Key words： amblyopia contrast sensitivity normal control children

Received: 17 August 2021

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Fund:Wuhan Municipal Health and Family Planning Commission (WX20D60); Aier Eye Hospital Group Scientific Research Fund(AM1908D1)

Corresponding Authors: Hongbin Dai, Strabismus Amblyopia and Pediatric Ophthalmology of Aier Ophthalmology Hospital Affiliated to Wuhan University, Wuhan 430061, China (Email:daihongbin2006@ sina.com)

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	Jingjing Zhou
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Cite this article:

Jingjing Zhou,Hongbin Dai,Youhua Zhang. The Difference in Contrast Sensitivity between Amblyopic Children and Normal Children[J]. Chinese Journal of Optometry Ophthalmology and Visual science, 2022, 24(4): 241-247.

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https://www.cjoovs.com/EN/10.3760/cma. j.cn115909-20210817-00322 OR https://www.cjoovs.com/EN/Y2022/V24/I4/241

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