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| Evaluation of Optical Performance of IOL in Vitro by Optical Bench |
| Guangliang Cao1, Xiaomin Liu2, Zheng Fan2, Zhichao Ren2, Yusen Huang2 |
| 1Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan 250117, China 2Qingdao Eye Hospital of Shandong First Medical University, Eye Institute of Shandong First Medical University, State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory ofOphthalmology, Qingdao 266071, China |
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Abstract Objective: To evaluate the optical performance of intraocular lens in vitro by optical bench. Methods: In this experimental study, the intraocular lens (IOL) with different optical performance was tested in vitro by optical bench OptiSpheric? IOL PRO Ⅱ . The spectral transmittance of Vivinex, SN60WF and ZCB00 were compared. The modulation transfer function (MTF) under different degrees of decentration and tilt were compared for Vivinex, A1-UV, SN60WF and ZCB00. The USAF resolution test charts and MTF of AT LISA tri, Diff-aAY, SBL-3, Symfony and ZCB00 were compared at the best distance, intermediate and near focus. The data were analyzed by one-way ANOVA and independent sample t-test. Results: Compared with non-blue-light filtering IOL ZCB00, blue-light filtering IOL Vivinex and SN60WF could significantly reduce the blue light transmission at the wavelength of 400-500 nm. In the wavelength range around 400 nm, the spectral transmittance of Vivinex was less than SN60WF, the difference was statistically significant (t=-15.65, P<0.001); in the wavelength range around 480 nm affecting melatonin secretion, the spectral transmittance of Vivinex was greater than SN60WF, the difference was statistically significant (t=11.04, P<0.001). When the IOL was decentrated or tilt in the same extent, the MTF values at 100 lp/mm spatial frequency of Vivinex and A1-UV were better than ZCB00 and SN60WF, the difference was statistically significant (all P<0.05). The best distance focus, ZCB00 had the highest MTF value and the best USAF resolution; the best intermediate focus, Symfony had the highest MTF value and the best USAF resolution; the best near focus, Diff-aAy has the highest MTF value and the best USAF resolution. When the defocus degree of monofocal IOL exceeded 0.50 D, the visual quality of resolving object details would decline more than that of multifocus IOL without defocus. Conclusions: The spectral transmittance of Vivinex and SN60WF are different. Vivinex and A1-UV are more tolerant to decentration and tilt than ZCB00 and SN60WF. Different types of multifocal IOLs have different optical quality at the distance, intermediate and near focus.
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Received: 18 November 2021
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| Fund:National Natural Science Foundation of China (81970788); Taishan Scholar Program(20190983); The Academic Promotion Program of Shandong First Medical University (2019ZL001) |
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Corresponding Authors:
Yusen Huang, Qingdao Eye Hospital of Shandong First Medical University,Eye Institute of Shandong First Medical University, State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Qingdao 266071, China (Email: huang_yusen@126.com)
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