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| The Changes of Functional Optical Zone after SMILE for the Correction of High Myopia andAstigmatism |
| Zhe Yang, Likun Xia |
| Department of Ophthalmology, Shengjing Hospital of China Medical University, Shenyang 110004, China |
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Abstract Objective: To analyze the changes of functional optical zone after the correction of high myopia and astigmatism using small incision lenticule extraction (SMILE), and explore the effect of functional optical zone on visual quality. Methods:In this prospective clinical study, 84 patients (84 eyes) with high myopia (spherical equivalent<-6.00D) who underwent SMILE in Shengjing Hospital of China Medical University from January 2022 to June 2022 were included. According to the predicted astigmatism, eyes were divided into three groups: no astigmatism group (astigmatism=0 D, 28 eyes); low astigmatism group (astigmatism≥-2.00 D, 30 eyes); high astigmatism group (astigmatism<-2.00 D, 26 eyes).The functional optical zone, corneal aberration, corneal curvature, and corneal Q value were measured by using a Scheimpfug camera preoperativelyand 3 months postoperatively. Data from the right eyes of all patients were analyzed in this study. Statistical analyses were performed using Chi-square test, one-way ANOVA, and Pearson correlation. Results:All of the optical zones were programmed at 6.5 mm. At 3 months after operation, the functional optical zone of the no astigmatism group, low astigmatism group, and high astigmatism group were 5.17±0.09 mm, 5.20±0.16 mm, and 5.34±0.15 mm, respectively. And the differenceamongthethreegroups was statisticallysignifcant(F=5.64, P=0.006).Thesizeof functional optical zone in the high astigmatismgroup was signifcantly higher than those in the no astigmatism group and low astigmatism group (P=0.025, 0.008). However, there was no signifcant difference between the no astigmatism and low astigmatism groups (P=0.403). There were signifcant differences in the size of functional optical zone at 0-180°, 30°-210°, 150°-330° meridian (F=7.82, P=0.001; F=3.32, P=0.043;F=6.56, P=0.003), and the functional optical zone in the high astigmatism group was significantly larger than those in the low astigmatism group and no astigmatism group (all P<0.05). But there were no differences in the size of functional optical zone in other meridians (allP>0.05) among the three groups. Therewerestatistically signifcantdifferences in thechangeofhigher order aberrations (HOAs)(F=3.35, P=0.042), and HOAs increased less in the high astigmatism group than in the low astigmatism group (P=0.021). There were no signifcant differencesin the changesof the spherical aberration (SA),horizontalComa, verticalComaand Trefoil(allP>0.05) among the three groups before and after surgery. Three months after surgery, the size of functional optical zone was negatively correlated with thechanges of HOAs, SA, Km, and cornealQ value(r=-0.39, P=0.002;r=-0.40, P=0.001;r=-0.47,P<0.001; r=-0.34, P=0.007). Conclusions:The functional optical zone was reduced compared with the preoperative predicted optical zone after SMILE. The eyes with high astigmatism had larger functional optical zone and less corneal aberration increase than those with low astigmatism. The changes of corneal curvatureand cornealasphericmorphology affectthesizeof functionalopticalzoneafter operation.
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Received: 17 September 2022
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| Fund:Key R&D Program Joint Program Project of Liaoning Province in 2020 (2020JH 2/10300135) |
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Corresponding Authors:
Likun Xia, Department of Ophthalmology, Shengjing Hospital of China Medical University, Shenyang 110004, China (Email: xialk@sj-hospital.org)
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| [1] |
Chinese Optometric Association, Chinese Ophthalmological Society; Ophthalmology and Optometry Committee, Ophthalmologists Association, Chinese Doctor Association; et al. Expert Consensus on Prevention and Control of High Myopia (2023)[J]. Chinese Journal of Optometry Ophthalmology and Visual science, 2023, 25(6): 401-407. |
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