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Abstract Objective To evaluate the effectiveness,safety and adaptability of prisms combined with plus lenses (PCPLs) on the progression of myopia in Chinese children.Methods One hundred seventy-one myopic Chinese children (ages 7-13,-0.50 to-3.00 D spherical refractive error)in the city of Guangzhou city whose parents did not have moderate or high myopia were enrolled in a 2 year prospective study.The children were assigned to 1 of 3 treatments:①single vision lens (SVLs) (n=89); ②PCPLs 1 (with +1.5 D add) (n=40) or ③PCPLs 2 (with +2.00 D add) (n=42).The primary outcomes,that included myopic progression,ocular biometry and heterophoria status,were assessed every 6 months.Results 75/89 children in the SVL group,28/40 in the PCPL 1 group and 31/42 in the PCPL 2 group completed the two-year study.The changes in phoria at distance were 0.22±1.97△,0.29±3.01△ and 0.13±2.16△ (Pgroup=0.17,Ptime＜0.01),respectively.The SER changes in the respective groups with SVLs,PCPLs 1 and PCPLs 2 were-1.50±0.67 D,-1.18±0.60 D and -1.04±0.66 D (P＜0.01),with axial length elongations of 0.74±0.43 mm,0.44±0.38 mm and 0.42±0.30 mm (P＜0.01).Conclusion The results of the two-year study show that,compared with SVLs,PCPLs can slow myopia progression and reduce the elongation of axial length.The adaptability to PCPLs is lower than SVLs and has no clinical effect on distance phoria.However,the long-term effect of PCPLs needs further study.
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