POAG患者黄斑区脉络膜厚度分析

doi:10.3760/cma.j.issn.1674-845X.2014.10.002

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Abstract

Objective To evaluate choroidal thickness （CT） at various macular locations in primary open angle glaucoma （POAG） and compare it to normal eyes. Methods This was a cross-sectional study. Choroidal imaging at various macular locations was performed by enhanced depth imaging optical coherence tomography （EDI-OCT） in 46 eyes of 46 POAG patients and 50 eyes of 50 age- and sex-matched normal subjects. Measurements were taken of the subfovea， and at 1 and 3 mm to the fovea superiorly， inferiorly， temporally， and nasally. CT between POAG and normal subjects was compared. Correlations were calculated for the variation in CT relative to age， intraocular pressure （IOP）， MD and other ocular parameters. Results In both groups， the subfoveal CT was the thickest and 3 mm to the fovea nasally was the thinnest （P＜0.05）. CT in different stages of POAG showed no significant differences. Compared to normal subjects， CT at all macular locations in POAG eyes did not differ. In POAG eyes， CT at the subfovea， I1 mm， N1 mm， N3 mm and average CT showed negative correlations with MD （r=-0.509， -0.515， -0.495， -0.480， -0.478， P＜0.05）. Conclusion The CT at different locations of POAG eyes has a similar distribution compared to normal eyes. However， a significant difference between POAG and normal subjects has not been found.

Key words： Glaucoma open-angle Choroidal thickness Tomography optical coherence

Received: 15 March 2014

Corresponding Authors: Zhang Xiulan，Email：xiulan_z@yahoo.com

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	Du Shaolin
	Wang Wei
	Zhang Xiulan
	Lin Shunchao

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Du Shaolin,Wang Wei,Zhang Xiulan等. Choroidal thickness at various macular locations in primary open-angle glaucoma[J]. Chinese Journal of Optometry Ophthalmology and Visual science, 2014, 16(10): 579-583.

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https://www.cjoovs.com/EN/10.3760/cma.j.issn.1674-845X.2014.10.002 OR https://www.cjoovs.com/EN/Y2014/V16/I10/579

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