Abstract Objective To investigate the retinal thickness of the macula in adult amblyopic and normal eyes with optical coherence tomography (OCT). Methods The eyes of 47 amblyopic patients (65 eyes total)and 35 normal people (70 eyes total) were examined horizontally and vertically with OCT. The mean thickness of the retinal foveola was measured. 700 μm and 1000 μm to the foveola was measured in the nasal, superior, temporal and inferior quadrants. The data were analyzed by the SPSS 10.0 software, using t test. Results The mean retinal thickness of the foveola and 700 μm away from the foveola in amblyopic eyes were (153.45±12.37)μm, (257.68±12.73)μm, (263.27±15.17)μm, (247.55±13.62)μm and (262.41±16.37)μm, respectively. The retinal thickness of corresponding positions in normal eyes was (142.27±9.61)μm, (251.39±16.29)μm, (254.92±13.83)μm, (240.27±14.54)μm and (256.71±15.81)μm, respectively. The mean retinal thickness of the foveola and 700 μm from the foveola in amblyopic eyes was significantly larger than that in normal eyes (t= 5.39, 2.49, 3.34, 2.99, 2.05, respectively. P<0.05). The mean retinal thickness of the foveola and 1000 μm from the foveola in amblyopic eyes were (262.09±13.67)μm, (266.46±12.76)μm, (252.11± 13.47)μm and (264.32±15.23)μm, respectively. The retinal thickness of the corresponding positions in normal eyes was (264.25±14.42)μm, (269.61 ±13.66)μm, (250.91 ±13.27)μm and (261.75±14.18)μm, respectively. There was no significant difference in the perimacular (1000 μm from the foveola) retinal thickness between amblyopic and normal eyes (t=0.89, 1.38, 0.52, 1.06, respectively. P>0.05). Conclusion Retinal thicknesses of the foveola and 700 μm from the foveola in amblyopic eyes are thicker than those in normal eyes. The retinal abnormality of the foveola and fovea may be related to amblyopia.
|