Abstract:Objective: To explore the significance of optical coherence tomography (OCT) in the early screening, intervention and follow-up of macular diseases in middle-aged and elderly people listed in the community health records. Methods: This was a retrospective study. From January 2016 to December 2017, 1 206 middle-aged and elderly people were selected from the Public Health Department of Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, including 520 males and 686 females, aged 50-82 years, with an average age of 58.3±5.7 years. The macular area of the eye was examined by OCT. The data were analyzed by a χ2 test and multivariate logistic regression analysis. Results: The coincidence rate of macular diseases was 17.91%. There was no significant difference between males and females in the OCT-positive population (χ2 =0.166, P=0.684). The positive rate of OCT was 8.48% in people aged 50-59, 18.43% in people aged 60-69 and 27.53% in people over 70 years of age. The differences were statistically significant (χ2 =36.269, P<0.001). Hypertension (OR=0.272, 95%CI=0.084-0.880, P=0.030) and diabetes (OR=0.131, 95%CI=0.039-0.440, P=0.001) were risk factors for macular disease. Conclusions: OCT is an indispensable method in preventing blindness since macular disease can be detected early and result in early intervention.
金慧瑜 邓建松 罗会舟. OCT在社区健康档案黄斑病变筛查中的应用[J]. 中华眼视光学与视觉科学杂志, 2020, 22(6): 455-458.
Huiyu Jin, Jiansong Deng, Huizhou Luo. The Application of Optical Coherence Tomography in Macular Lesion Screenings from Community Health Records. Chinese Journal of Optometry Ophthalmology and Visual science, 2020, 22(6): 455-458. DOI: 10.3760/cma.j.cn115909-20190902-00240
Fernández-Robredo P, Sancho A, Johnen S, et al. Current treatment limitations in age-related macular degeneration and future approaches based on cell therapy and tissue engineering. J Ophthalmol, 2014, 2014: 510285. DOI: 10.1155/2014/510285.
[8]
Fleckenstein M, Mitchell P, Freund KB, et al. The progression of geographic atrophy secondary to age-related macular degeneration. Ophthalmology, 2018, 125(3): 369-390. DOI: 10.1016/j.ophtha.2017.08.038.
[9]
Chen CY, Wong TY, Heriot WJ. Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration: A short-term study. Am J Ophthalmol, 2007, 143(3): 510-512. DOI: 10.1016/j.ajo.2006.10.004.
Peyman M, Tajunisah I, Loo A, et al. Scanning laser edema index: A reliable tool to correlate with diabetic retinopathy and systemic risk factors. J Diabetes Complications, 2012, 26(3): 210-213. DOI: 10.1016/j.jdiacomp.2012.03.019.
Guariguata L, Whiting DR, Hambleton I, et al. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract, 2014, 103(2): 137-149. DOI: 10.1016/ j.diabres.2013.11.002.
[15]
Wang J, Zhang L, Wang F, et al. Prevalence, awareness, treatment, and control of hypertension in China: Results from a national survey. Am J Hypertens, 2014, 27(11): 1355-1361. DOI: 10.1093/ajh/hpu053.