The pathogenesis of thyroid-associated ophthalmopathy (TAO) is still unclear.Researches show that the abnormal expansion of orbital adipose tissue is a leading cause of thyroidassociated ophthalmopathy,of which studies are made by both Chinese and overseas researchers and into which some new insights are gained.This article makes a comprehensive review of the progress of researches in terms of the source of orbital preadipocytes,the regulation of adipogenesis,and the expression and role of peroxisome proliferators-activated receptor gamma (PPARγ) and thyroid stimulating hormone receptor (TSHR) in the orbital adipose tissue of the TAO patients.
赵平千,范先群. 眼眶前脂肪细胞在甲状腺相关眼病中的作用研究进展[J]. 中华眼视光学与视觉科学杂志, 2012, 14(5): 317-319.
ZHAO Ping-qian,FAN Xian-qun. The research progress of the role of orbital preadipocytes in thyroid-associated ophthalmopathy. Chinese Journal of Optometry Ophthalmology and Visual Science, 2012, 14(5): 317-319. DOI: 10.3760/cma.j.issn.1674-845X.2012.05.016