Objective To investigate the efficacy and safety of posterior chamber phakic refractive lens (PC-PRL) implants for high myopia. Methods A retrospective case study of phakic intraocular lens implantation was carried out on high myopia patients. Thirty-eight patients (68 eyes) with high myopia (-11.25 to -20.00 D) were implanted with PC-PRLs. Preoperative and postoperative visual acuity, intraocular pressure, corneal endothelial cell count, anterior chamber depth and intraocular lens position were observed and analyzed. The differences between postoperative equivalent spherical errors were analyzed in different refractive error groups with repeated measure ANOVA. Results All patients gained uncorrected visual acuity ≥4.7 in 6 months, which was equal to or better than preoperative best corrected visual acuity. Seven patients (10 eyes) had early high postoperative intraocular pressure. The intraocular pressure returned to a normal level after treatment. All patients had decreased anterior chamber depth postoperatively(F=32.952, P<0.01). Horizontal/vertical trabecular iris angle, angle opening distance, and arch height did not significantly change (P>0.05) in all implanted eyes. No iris bombe or angle block was detected in any patient. Postoperative IOL position and distance from the lens remained stable during the follow-up period. Conclusion Posterior chamber phakic refractive lens implantation for high myopia is a precise and safe procedure with good predictability.
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