OCT在社区健康档案黄斑病变筛查中的应用

doi:10.3760/cma.j.cn115909-20190902-00240

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Abstract Objective: To explore the significance of optical coherence tomography (OCT) in the early screening, intervention and follow-up of macular diseases in middle-aged and elderly people listed in the community health records. Methods: This was a retrospective study. From January 2016 to December 2017, 1 206 middle-aged and elderly people were selected from the Public Health Department of Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, including 520 males and 686 females, aged 50-82 years, with an average age of 58.3±5.7 years. The macular area of the eye was examined by OCT. The data were analyzed by a χ2 test and multivariate logistic regression analysis. Results: The coincidence rate of macular diseases was 17.91%. There was no significant difference between males and females in the OCT-positive population (χ2 =0.166, P=0.684). The positive rate of OCT was 8.48% in people aged 50-59, 18.43% in people aged 60-69 and 27.53% in people over 70 years of age. The differences were statistically significant (χ2 =36.269, P<0.001). Hypertension (OR=0.272, 95%CI=0.084-0.880, P=0.030) and diabetes (OR=0.131, 95%CI=0.039-0.440, P=0.001) were risk factors for macular disease. Conclusions: OCT is an indispensable method in preventing blindness since macular disease can be detected early and result in early intervention.

Key words： optical coherence tomography retina macular diseasescreening

Received: 02 September 2019

Corresponding Authors: Huiyu Jin, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430077, China (Email: 1608661995@qq.com)

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https://www.cjoovs.com/EN/ 10.3760/cma.j.cn115909-20190902-00240 OR https://www.cjoovs.com/EN/Y2020/V22/I6/455

[1]	丁波, 过贵元, 孙桂珍, 等. 光学相干断层成像在眼科视网膜黄斑部体检中的应用. 东南国防医药, 2015, 17(4): 356-357, 401. DOI: 10.3969/j.issn.1672-271X.2015.04.006.
[2]	卓耀, 彭廷云. 启明丸治疗年龄相关性黄斑变性的临床疗效及对血浆Hcy水平的影响. 中国中医眼科杂志, 2013, 23(1): 36-38. DOI: 10.13444/j.cnki.zgzyykzz.003085.
[3]	Sayanagi K, Morimoto Y, Ikuno Y, et al. Spectral-domain optical coherence tomographic findings in myopic foveoschisis. Retina, 2010, 30(4): 623-628. DOI: 10.1097/iae.0b013e3181ca4e7c.
[4]	李泽斌. 光学相干断层扫描在病理性近视黄斑病变中的应用. 医学综述, 2012, 18(10): 1575-1577.
[5]	向伟, 李慧平, 刘洋, 等. 宁夏同心县≥50岁人群年龄相关性黄斑变性患病率、危险因素及致盲情况分析. 宁夏医科大学学报, 2015, 37(8): 927-930. DOI: 10.16050/j.cnki.issn1674- 6309.2015.08.016.
[6]	黄晓波. 老年性黄斑变性患者光学断层成像与荧光素眼底造影结果分析. 海南医学, 2015, 26(22): 3380-3381. DOI: 10.3969/j.issn.1003-6350.2015.22.1226.
[7]	Fernández-Robredo P, Sancho A, Johnen S, et al. Current treatment limitations in age-related macular degeneration and future approaches based on cell therapy and tissue engineering. J Ophthalmol, 2014, 2014: 510285. DOI: 10.1155/2014/510285.
[8]	Fleckenstein M, Mitchell P, Freund KB, et al. The progression of geographic atrophy secondary to age-related macular degeneration. Ophthalmology, 2018, 125(3): 369-390. DOI: 10.1016/j.ophtha.2017.08.038.
[9]	Chen CY, Wong TY, Heriot WJ. Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration: A short-term study. Am J Ophthalmol, 2007, 143(3): 510-512. DOI: 10.1016/j.ajo.2006.10.004.
[10]	苏鹏, 晏世刚, 孔祥斌, 等. 光学相干断层扫描在老年性黄斑变性诊断中的应用价值研究. 中国医药科学, 2016, 6(4): 192- 194, 202.
[11]	Peyman M, Tajunisah I, Loo A, et al. Scanning laser edema index: A reliable tool to correlate with diabetic retinopathy and systemic risk factors. J Diabetes Complications, 2012, 26(3): 210-213. DOI: 10.1016/j.jdiacomp.2012.03.019.
[12]	曹曦, 袁明霞, 信中, 等. 北京市昌平区自然人群黄斑病变情况调查及分析. 首都医科大学学报, 2015, (6): 853-856. DOI: 10.3969/j.issn.1006-7795.2015.06.004.
[13]	张厚洪. 角膜内皮细胞变化与糖尿病性视网膜病变分期的关系. 新乡医学院学报, 2014, 31(10): 842-844. DOI: 10.7683/ xxyxyxb.2014.10.022.
[14]	Guariguata L, Whiting DR, Hambleton I, et al. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract, 2014, 103(2): 137-149. DOI: 10.1016/ j.diabres.2013.11.002.
[15]	Wang J, Zhang L, Wang F, et al. Prevalence, awareness, treatment, and control of hypertension in China: Results from a national survey. Am J Hypertens, 2014, 27(11): 1355-1361. DOI: 10.1093/ajh/hpu053.
[16]	林艳珍. 血塞通软胶囊治疗高血压性视网膜病的疗效观察. 中医临床研究, 2013, 5(19): 90-91. DOI: 10.3969/j.issn.1674- 7860.2013.19.053.
[17]	钱波, 张艳. 中老年健康体检人群眼底动脉硬化与高血压相关性分析. 心血管康复医学杂志, 2012, 21(1): 45-46. DOI: 10.3969/j.issn.1008-0074.2012.01.14. [18] 吴宇霏, 谭凡, 郑玥, 等. 2型糖尿病患者早期黄斑区视网膜亚层及脉络膜的光学相干断层扫描成像特征. 中华眼视光学与视觉科学杂志, 2018, 20(11): 663-668. DOI: 10.3760/cma. j.issn.1674-845X.2018.11.005.