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Comparative Study of the Progression of Low to Moderate Myopia in Children 6−12 Years of Age in the Xi'an First Hospital before and after the Outbreak of COVID-19 |
Pan Li, Tong Li, Jin Wang, Ruoxin Wang, Xuehui Zhang |
Department of Ophthalmology, Xi'an First Hospital, Institute of Ophthalmology, Key Lab of Ophthalmology, Clinical Center for Ophthalmology, Xi'an 710002, China |
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Guide |
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Abstract Objective: To compare the progression of low to moderate myopia in children 6-12 years of age in
the Xi'an First Hospital before and after the COVID-19 epidemic. Methods: This was a retrospective
cohort study. One hundred cases (200 eyes) of children 6-12 years of age with binocular myopia who
were admitted to the Department of Ophthalmology in Xi'an No.1 Hospital before the outbreak of the COVID-19 epidemic (December 2018 to January 2019) and after the outbreak (December 2019 to January
2020) participated in the study. Follow-up records were recorded for 0.5 and 1 year. The mean age of the
pre-epidemic group was 9.6±1.2 years, and the mean age of the post-epidemic group was 9.2±2.4 years.
Changes in the ocular axis (AL), spherical equivalent (SE) and axial/corneal curvature ratio (AL/CR) at
baseline, 0.5 and 1 year were retrospectively analyzed in the 2 groups, and the data were compared by a
paired t test. Results: At the 0.5 year follow-up, the pre-epidemic group showed less AL growth than the
post-epidemic group (0.27±0.16 mm vs. 0.36±0.19 mm) (t=-6.228, P<0.001), an increase in SE (-0.48±
0.37 D vs. -0.74±0.63 D) (t=-2.375, P<0.001), and an increase in AL/CR ratio (0.017±0.028 vs.
0.029±0.031) (t=-6.052, P<0.001). At the 1 year follow-up, the pre-epidemic group showed less AL growth
than the post-epidemic group (0.46±0.31 vs. 0.61±0.24) (t=1.138, P<0.001), an increase in SE (-0.90±
0.41 D vs. -1.25±0.48 D) (t=7.253, P<0.001), and an increase in the AL/CR ratio (0.030±0.051 vs.
0.046±0.036) (t=5.049, P=0.032). Conclusions: After the outbreak of COVID-19, the progression of
myopia in 6-12 year-old school-age children in the post-epidemic is faster than in the pre-epidemic, mainly
manifested in AL, SE and AL/CR
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Received: 19 May 2021
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Fund: |
Corresponding Authors:
Xuehui Zhang, Department of Ophthalmology, Xi'an First Hospital, Institute of Ophthalmology, Key Lab of Ophthalmology, Clinical Center for Ophthalmology, Xi'an 710002, China (Email:1346841463@qq.com)
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[1] |
Wang G, Zhang Y, Zhao J, et al. Mitigate effects of homeconfinement on children during the COVID-19 outbreak.Lancet, 2020, 395(10228): 945-947. DOI: 10.1016/S0140-6736(20)30547-X.
|
[2] |
Lingham G, Mackey DA, Lucas R, et al. How doesspending time outdoors protect against myopia? A review.Br J Ophthalmol, 2020, 104(5): 593-599. DOI: 10.1136/bjophthalmol-2019-314675.
|
[3] |
Wen L, Cao Y, Cheng Q, et al. Objectively measurednear work, outdoor exposure and myopia in children. Br J Ophthalmol, 2020, 104(11): 1542-1547. DOI: 10.1136/bjophthalmol-2019-315258.
|
[4] |
Jee D, Morgan IG, Kim EC. Inverse relationship between sleepduration and myopia. Acta Ophthalmol, 2016, 94(3): e204-210.DOI: 10.1111/aos.12776.
|
[5] |
Ayaki M, Torii H, Tsubota K, et al. Decreased sleep quality inhigh myopia children. Sci Rep, 2016, 6: 33902. DOI: 10.1038/srep33902.
|
[6] |
Zhou Z, Morgan IG, Chen Q, et al. Disordered sleep and myopiarisk among Chinese children. PLoS One, 2015, 10(3): e0121796.DOI: 10.1371/journal.pone.0121796.
|
[7] |
GBD 2016 Disease and Injury Incidence and PrevalenceCollaborators. Global, regional, and national incidence,prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet, 2017,390(10100): 1211-1259. DOI: 10.1016/S0140-6736(17)32154-2.
|
[8] |
陈军, 何鲜桂, 王菁菁, 等. 2021 至2030 年我国6~18 岁学生近视眼患病率预测分析. 中华眼科杂志, 2021, 57(4): 261-267.DOI: 10.3760/cma.j.cn112142-20201228-000851.
|
[9] |
Chen L, Deng C, Chen X, et al. Ocular manifestations andclinical characteristics of 535 cases of COVID-19 in Wuhan,China: a cross-sectional study. Acta Ophthalmol, 2020, 98(8):e951-959. DOI: 10.1111/aos.14472.
|
[10] |
Ma Y, Zou H, Lin S, et al. Cohort study with 4-year follow-up ofmyopia and refractive parameters in primary schoolchildren in Baoshan District, Shanghai. Clin Exp Ophthalmol, 2018, 46(8):861-872. DOI: 10.1111/ceo.13195.
|
[11] |
Wu PC, Chen CT, Lin KK, et al. Myopia Prevention andOutdoor Light Intensity in a School-Based Cluster Randomized Trial. Ophthalmology, 2018, 125(8): 1239-1250. DOI: 10.1016/j.ophtha.2017.12.011.
|
[12] |
Donovan L, Sankaridurg P, Ho A, et al. Myopia progression ratesin urban children wearing single-vision spectacles. Optom Vis Sci, 2012, 89(1): 27-32. DOI: 10.1097/OPX.0b013e3182357f79.
|
[13] |
Zhou WJ, Zhang YY, Li H, et al. Five-year progression ofrefractive errors and incidence of myopia in school-aged children in Western China. J Epidemiol, 2016, 26(7): 386-395.DOI: 10.2188/jea.JE20140258.
|
[14] |
Xu L, Ma Y, Yuan J, et al. COVID-19 Quarantine RevealsGrade-specific Behavioral Modification of Myopia: One-Million Chinese Schoolchildren Study. medRxiv (18 November 2020).DOI: 10.1101/2020.11.15.20231936.
|
[15] |
He X, Zou H, Lu L, et al. Axial length/corneal radius ratio:association with refractive state and role on myopia detection combined with visual acuity in Chinese schoolchildren.PLoS One, 2015, 10(2): e0111766. DOI: 10.1371/journal.pone.0111766.
|
[16] |
You X, Wang L, Tan H, et al. Near Work Related Behaviors Associated with Myopic Shifts among Primary School Students in the Jiading District of Shanghai: A School-Based One-Year Cohort Study. PLoS One, 2016, 11(5): e0154671. DOI: 10.1371/journal.pone.0154671.
|
[17] |
Liu L, Jiang D, Li C, et al. Relationship between myopia progression and school entrance age: A 2.5-Year Longitudinal Study. J Ophthalmol, 2021, 2021: 7430576. DOI: 10.1155/2021/7430576.
|
[18] |
He M, Xiang F, Zeng Y, et al. Effect of time spent outdoors at school on the development of myopia among children in China: a randomized clinical trial. JAMA, 2015, 314(11): 1142-1148.DOI: 10.1001/jama.2015.10803.
|
[19] |
Jin JX, Hua WJ, Jiang X, et al. Effect of outdoor activity on myopia onset and progression in school-aged children in northeast China: the Sujiatun Eye Care Study. BMC Ophthalmol, 2015, 15: 73. DOI: 10.1186/s12886-015-0052-9.
|
[20] |
Li SM, Li SY, Kang MT, et al. Near Work Related ParametersChinese Schoolchildren Study. medRxiv (18 November 2020).DOI: 10.1101/2020.11.15.20231936.
|
[15] |
He X, Zou H, Lu L, et al. Axial length/corneal radius ratio:association with refractive state and role on myopia detection combined with visual acuity in Chinese schoolchildren.PLoS One, 2015, 10(2): e0111766. DOI: 10.1371/journal.pone.0111766.
|
[16] |
You X, Wang L, Tan H, et al. Near Work Related BehaviorsAssociated with Myopic Shifts among Primary School Students in the Jiading District of Shanghai: A School-Based One-Year Cohort Study. PLoS One, 2016, 11(5): e0154671. DOI: 10.1371/journal.pone.0154671.
|
[17] |
Liu L, Jiang D, Li C, et al. Relationship between myopiaprogression and school entrance age: A 2.5-Year Longitudinal Study. J Ophthalmol, 2021, 2021: 7430576. DOI: 10.1155/2021/7430576.
|
[18] |
He M, Xiang F, Zeng Y, et al. Effect of time spent outdoors atschool on the development of myopia among children in China: a randomized clinical trial. JAMA, 2015, 314(11): 1142-1148.DOI: 10.1001/jama.2015.10803.
|
[19] |
Jin JX, Hua WJ, Jiang X, et al. Effect of outdoor activityon myopia onset and progression in school-aged children in northeast China: the Sujiatun Eye Care Study. BMC Ophthalmol, 2015, 15: 73. DOI: 10.1186/s12886-015-0052-9.
|
[20] |
Li SM, Li SY, Kang MT, et al. Near Work Related Parameters
|
|
|
|