1 Ophthalmology Department, Luoyang Maternal and Child Health Care Hospital, Luoyang 471000, China 2 Dongfang Hospital of Beijing University of Traditional Chinese Medicine, Beijing 100000, China
Abstract: Objective: To evaluate the ocular surface condition of children with uncorrected myopia by clinical examinations. Methods: This was a case control study. Thirty children with uncorrected myopia (60 eyes) were randomly selected as the study group and 30 normal children (60 eyes) as the control group. The ocular surface and meibomian gland condition were compared and evaluated with a slit lamp microscope. The observed data was evaluated by a non-parametric test. A spearman rank correlation analysis was used to evaluate the correlation between the ocular surface parameters in the observation group. Results: There was no significant difference in age, sex or lacrimal secretion between the two groups. There were statistically significant differences between the two groups in meibomian gland orifice scores (Z=-4.08, P<0.001), meibomian gland secretion scores (Z=-2.99, P=0.003), corneal fluorescein scores (Z=-2.65, P=0.008) and BUT (Z=-7.09, P<0.001). Negative correlations were found between BUT and meibomian gland orifice scores (rs=-0.501, P<0.001), meibomian gland secretion scores (rs=-0.400, P=0.002), and Marx's line scores (rs=-0.557, P<0.001), and there were no correlations between Marx's line scores, meibomian gland secretion scores with corneal fluorescein scores and a positive correlation was found between corneal fluorescein scores and meibomian gland orifice scores in children with uncorrected myopia (rs=0.332, P=0.012). Conclusions: The children with uncorrected myopia may have a high incidence of impairment in the meibomian gland and are a risk group for meibomian gland dysfunction.
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