眼针疗法治疗“气阴两虚型”干眼的临床研究

doi:10.3760/cma.j.cn115909-20210611-00237

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摘要目的：观察眼针疗法治疗“气阴两虚型”干眼的临床疗效及其作用机制。方法：前瞻性随机对照研究。收集2021年1—4月于辽宁中医药大学附属第二医院确诊为“气阴两虚型”干眼患者74例，通过随机数字表法将74例患者分为眼针疗法组和常规针法组，各37例。常规针法组给予常规针刺治疗，主穴为攒竹、四白、阳白、丝竹空、太阳；配穴为太溪、合谷、足三里、三阴交。眼针疗法组予以眼针治疗，取肝区、肺区、脾区、肾区四穴治疗。疗程均为14 d。记录2组治疗前后眼表疾病指数（OSDI）评分；检测无表麻泪液分泌试验（SⅠT）和角膜荧光素染色（CFS）；使用K5M眼表分析仪采集首次泪膜破裂时间（NIBUTf）和平均泪膜破裂时间（NIBUTav）。数据采用t检验、Wilcoxon秩和检验、χ2 检验进行统计分析。结果：常规针法组与眼针疗法组的OSDI评分、SⅠT、CFS、NIBUTf、 NIBUTav在组内治疗前后比较，差异均有统计学意义（均P<0.05）。治疗后2组患者的OSDI评分、 SⅠT、NIBUTf、NIBUTav比较，差异均有统计学意义（均P<0.05）；治疗后组间CFS比较差异无统计学意义。结论：常规针法与眼针疗法均能有效治疗“气阴两虚型”干眼，眼针疗法在改善干眼的眼表症状、泪液分泌及泪膜破裂时间方面优于常规针法治疗，其优效性和依从性更高。

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关键词 ：眼针, 干眼, 针刺, 气阴两虚

Abstract：Objective: Observing the clinical efficacy of ocular acupuncture in the treatment of dry eye due to the deficiency of Qi and Yin, and to explore its mechanism. Methods: In this prospective study, 74 patients with dry eye due to the deficiency of Qi and Yin from the Second Affiliated Hospital of Liaoning University of TCM were recruited from January to April 2021. Seventy-four patients were randomly divided into an ocular acupuncture group and a conventional acupuncture group, 37 patients in each group. The conventional acupuncture group was treated with conventional acupuncture; the ocular acupuncture therapy group received ocular acupuncture therapy, and 4 acupoints were taken from the liver, lung, spleen and kidney regions. The course of treatment was 14 days. The ocular surface disease index (OSDI) score before and after treatment was recorded. The Schirmer Ⅰ test (SⅠT) and corneal fluorescein staining (CFS) were used for assessment. The non-invasive first tear film break-up (NIBUTf) and non-invasive average tear film break-up (NIBUTav)were measured by the K5M ocular surface analyzer. Data were analyzed by the t test, Wilcoxon test and Chi-square test. Results: The OSDI score, S Ⅰ T, NIBUTf, NIBUTav and CFS of the two groups were significantly different before and after treatment (P<0.05). After treatment, the OSDI score, S Ⅰ T, NIBUTf, and NIBUTav of the two groups were significantly different (P<0.05). There was no significant difference in CFS between the two groups after treatment. Conclusion: Both ocular acupuncture and conventional acupuncture can effectively treat dry eye due to the deficiency of Qi and Yin. Ocular acupuncture is superior to conventional acupuncture in improving ocular surface symptoms, tear secretion and tear film rupture time of dry eye patients, with a higher efficacy and compliance.

Key words： eye acupuncture dry eye acupuncture deficiency of Qi and Yin

收稿日期: 2021-06-11

PACS:

基金资助:

国家中医药管理局“中医药循证能力建设项目”（2019XZZX-YK008）；
辽宁省自然科学基金（20170540557）

通讯作者: 左韬（ORCID：0000-0001-8734-7979），Email：ykzt208@163.com

引用本文:

赵磊, 迟凯耀, 周慧敏, 等.. 眼针疗法治疗“气阴两虚型”干眼的临床研究[J]. 中华眼视光学与视觉科学杂志, 2022, 24(4): 309-313. Lei Zhao1, Kaiyao Chi2, Huimin Zhou2, et al. Clinical Study of Ocular Acupuncture Therapy for Dry Eye due to the Deficiency of Qi and Yin. Chinese Journal of Optometry Ophthalmology and Visual science, 2022, 24(4): 309-313. DOI: 10.3760/cma.j.cn115909-20210611-00237

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https://www.cjoovs.com/CN/10.3760/cma.j.cn115909-20210611-00237 或 https://www.cjoovs.com/CN/Y2022/V24/I4/309

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