There are different techniques or methods to record visual or retinal function changes in laboratory animals. Clinical visual electrophysiological testing is a non-invasive diagnostic method that can record animal visual function in vivo. It can be used as a tool to investigate the visual physiological phenomena. It is also taken as an objective indicator to monitor visual function changes, such as the effect of various factors (whether physical, chemical or biological) on visual functions, evaluation of therapeutic efficiency, diagnosis for disease or drug development. There are many factors that might affect visual electrophysiological testing results so experimental control studies are necessary. The investigation of the new methods, indicators and analysis methods are the focus of research in this field. Establishing a standard experimental methodology is crucial for the technique to become widespread with good quality control.