Department of Ophthalmology, Beijing Tongren Hospital of Capital Medical University, Beijing 100730, China
Department of Ophthalmology, Beijng Children's Hospital, Capital Medical University, Beijing 100045, China
Department of Ophthalmology, Children's Hospital, Capital Institute of Pediatrics, Beijing 100020, China Department of Ophthalmology, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078,China
Department of Ophthalmology, Peking University International Hospital, Beijing 102206, China
Department of Ophthalmology, Peking University Third Hospital, Beijing 100083, China
Eye Hospital of China Academy of Chinese Medical Sciences, Beijing 100040, China Department of Ophthalmology, Beijing Ren He Hospital, Beijing 102600, China
Department of Ophthalmology, Beijing Tian Tan Hospital of Capital Medical University, Beijing 100050, China
Objective: To analyze refractive status and visual acuity and its relationship to binocular visual function in children with anisometropic amblyopia. Methods: A total of 106 children (106 eyes) with anisometropic amblyopia were recruited from November 2015 to September 2016 in nine hospitals in Beijing. All children were divided into the following groups based on risk factors for anisometropia: hyperopia anisometropia(67 cases), myopia anisometropia (5 cases), astigmatism anisometropia (12 cases), hyperopia combined astigmatism anisometropia (20 cases) and myopia combined astigmatism anisometropia (2 cases). Visual acuity, uncorrected and best corrected visual acuity, refractive status, and distant/near stereoscopic vision were tested. Pearson's correlation was used to analyze the correlation between dioptric differences and UCVA/BCVA in high refractive errors eye and distant/near stereoscopic vision. The correlation between BCVA difference of the two eyes and distant/near stereoscopic vision were also calculated. One-way ANOVA compared BCVA in high myopic eye and distant/near stereoscopic vision between groups.Results: There was a correlation for the dioptric difference between UCVA and BCVA, distant stereoscopic vision, and random dot stereograms (RDS) stereoscopic vision in high refractive errors (all P<0.05).There was a significant correlation between the difference in BCVA and distant stereoscopic vision and RDS stereoscopic vision (all P<0.05). There was a statistically significant difference between the five groups for BCVA, distant stereoscopic vision and RDS stereoscopic vision (F=6.221, 5.271, 3.622, 3.647,3.464, P<0.05). Visual acuity for high refractive error eye in the myopia anisometropia group was best compared to the other four groups. The differences were statistically significant between each group (all P<0.05). Distant stereoscopic vision in the hyperopia anisometropia group was best compared to the other four groups. The differences were statistically significant between each group, except hyperopia combined astigmatism anisometropia and myopia combined astigmatism anisometropia groups (all P<0.05). RDS stereopsis in the myopia anisometropia group was best compared to the other four groups. The differences were statistically significant between each group (all P<0.05). Conclusions: Visual acuity and stereoscopic vision are correlated to the dioptric difference. Stereoscopic vision is significantly correlated with the difference in BCVA. Stereoscopic damage is different in patients based on the type of anisometropia.
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