Excimer laser surface ablation refractive surgery can retain more corneal stromal tissue, has more stable corneal biomechanics and is effective in reducing refractive error. Patients with specific ocular conditions, such as a thinner cornea, corneal scars or previous radial keratotomy will have the best outcomes with surface ablation. However, postoperative pain caused by the healing process is the main problem that concerns doctors and patients. So postoperative pain still needs to be resolved. Pain control after corneal surface ablation is reviewed in this paper.
王璐,王雁. 角膜表层屈光手术后疼痛控制的研究进展[J]. 中华眼视光学与视觉科学杂志, 2014, 16(1): 57-60.
Wang Lu,Wang Yan. Current progress in pain control after corneal surface ablation. Chinese Journal of Optometry Ophthalmology and Visual Science, 2014, 16(1): 57-60. DOI: 10.3760/cma.j.issn.1674-845X.2014.01.014
Zhang Y, Chen YG, Xia YJ, et al. Comparison of tear cytokines and clinical outcomes between off-flap and on-flap epi-LASIK With mitomycin C[J]. J Refract Surg,2012,28:632-638.
[4]
Magone MT, Engle AT, Easter TH, et al. Flap-off epi-LASIK versus automated epithelial brush in PRK: a prospective comparison study of pain and reepithelialization times[J]. J Refract Surg,2012,28:682-688.
[5]
Torres LF, Sancho C, Tan B, et al. Early postoperative pain following Epi-LASIK and photorefractive keratectomy: A prospective, comparative, bilateral study[J]. J Refract Surg,2007,23:126-132.
Aslanides IM, Padroni S, Mosquera SA. Comparison of single-step reverse transepithelial all-surface laser ablation (ASLA) to alcohol-assisted photorefractive keratectomy[J]. Clin Ophthalmol,2012,26:973-979.
[8]
Doherty M, Kirwan C, Keeffe M. Postoperative pain following Epi-LASIK, LASEK, and PRK for myopia[J]. J Refract Surg,2007,23:133-138.
[9]
Sher NA, Frantz JM, Talley A, et al. Topical diclofenac in the treatment of ocular pain after excimer photorefractive keratectomy[J]. Refract Corneal Surg,1993,9:425-436.
[10]
Solomon KD, Donnenfeld ED, Raizman M, et al. Safety and efficacy of ketorolac tromethamine 0.4% ophthalmic solution in post-photorefractive keratectomy patients[J]. J Cataract Refract Surg,2004,30:1653-1660.
[11]
Colin J, Paquette B. Comparison of the analgesic efficacy and safety of nepafenac ophthalmic suspension compared with diclofenac ophthalmic solution for ocular pain and photophobia after excimer laser surgery: a phaseII, randomized, double-masked trial[J]. Clinical Therapeutics,2006,28:527-536.
[12]
Wang XJ, Wong SH, Givergis R, et al. Evaluation of analgesic efficacy of bromfenac sodium ophthalmic solution 0.09% versus ketorolac tromethamine ophthalmic solution 0.5% following LASEK or Epi-LASIK[J]. Clin Ophthalmol,2011,5:1451-1457.
[13]
Congdon NG, Schein OD, Kulajta PV, et al. Corneal complications associated with topical ophthalmic use of nonsteroidal antiinflammatory drugs[J]. J Cataract Refract Surg,2001,27:622-631.
[14]
Reviglio VE, Rana TS, Li QJ, et al. Effects of topical non-steroidal antiinflammatory drugs on the expression of matrix metalloproteinases in the cornea[J]. J Cataract Refract Surg,2003,29:989-997.
[15]
Razmjoo H, Abdi E, Atashkadi S, et al. Comparative study of two silicone hydrogel contact lenses used as bandage contact lenses after photorefractive keratectomy[J]. Int J Prev Med,2012,3:718-722.
[16]
Kirwan C, Mulqueen C, Keefe MO. A double-blind randomized control study to determine the effect of VisthesiaTM viscoelastic substance on pain following LASEK[J]. Ophthalmologica,2008, 222:229-231.
[17]
Trattler WB, Barnesb SD. Current trends in advanced surface ablation[J]. Curr Opin Ophthalmol,2008,19:330-334.
[18]
Nissman SA, Tractenberg RE, Babbar GA, et al. Oral gabapentinfor the treatment of postoperative pain after photorefractive keratectomy[J]. Am J Ophthalmol,2008,145:623-629.