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binocular Vision Function in Children with Anisometropic Amblyopia |
Bowen Zhao,Jing Fu,Jie Hong,Li Li,Suhong Yang,Lei Li,Jian Zhou,Lejin Wang,Juan Bu,Leiyan Su,Yingjun Han, Min Fang,Wen Liu,Hao Zhang |
Department of Ophthalmology, Beijing Tongren Hospital of Capital Medical University, Beijing 100730, China
Department of Ophthalmology, Beijng Children's Hospital, Capital Medical University, Beijing 100045, China
Department of Ophthalmology, Children's Hospital, Capital Institute of Pediatrics, Beijing 100020, China Department of Ophthalmology, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078,China
Department of Ophthalmology, Peking University International Hospital, Beijing 102206, China
Department of Ophthalmology, Peking University Third Hospital, Beijing 100083, China
Eye Hospital of China Academy of Chinese Medical Sciences, Beijing 100040, China Department of Ophthalmology, Beijing Ren He Hospital, Beijing 102600, China
Department of Ophthalmology, Beijing Tian Tan Hospital of Capital Medical University, Beijing 100050, China |
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Abstract Objective: To analyze refractive status and visual acuity and its relationship to binocular visual function in children with anisometropic amblyopia. Methods: A total of 106 children (106 eyes) with anisometropic amblyopia were recruited from November 2015 to September 2016 in nine hospitals in Beijing. All children were divided into the following groups based on risk factors for anisometropia: hyperopia anisometropia(67 cases), myopia anisometropia (5 cases), astigmatism anisometropia (12 cases), hyperopia combined astigmatism anisometropia (20 cases) and myopia combined astigmatism anisometropia (2 cases). Visual acuity, uncorrected and best corrected visual acuity, refractive status, and distant/near stereoscopic vision were tested. Pearson's correlation was used to analyze the correlation between dioptric differences and UCVA/BCVA in high refractive errors eye and distant/near stereoscopic vision. The correlation between BCVA difference of the two eyes and distant/near stereoscopic vision were also calculated. One-way ANOVA compared BCVA in high myopic eye and distant/near stereoscopic vision between groups.Results: There was a correlation for the dioptric difference between UCVA and BCVA, distant stereoscopic vision, and random dot stereograms (RDS) stereoscopic vision in high refractive errors (all P<0.05).There was a significant correlation between the difference in BCVA and distant stereoscopic vision and RDS stereoscopic vision (all P<0.05). There was a statistically significant difference between the five groups for BCVA, distant stereoscopic vision and RDS stereoscopic vision (F=6.221, 5.271, 3.622, 3.647,3.464, P<0.05). Visual acuity for high refractive error eye in the myopia anisometropia group was best compared to the other four groups. The differences were statistically significant between each group (all P<0.05). Distant stereoscopic vision in the hyperopia anisometropia group was best compared to the other four groups. The differences were statistically significant between each group, except hyperopia combined astigmatism anisometropia and myopia combined astigmatism anisometropia groups (all P<0.05). RDS stereopsis in the myopia anisometropia group was best compared to the other four groups. The differences were statistically significant between each group (all P<0.05). Conclusions: Visual acuity and stereoscopic vision are correlated to the dioptric difference. Stereoscopic vision is significantly correlated with the difference in BCVA. Stereoscopic damage is different in patients based on the type of anisometropia.
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Received: 25 December 2017
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Fund: Technology Achievements and Appropriate Technology Promotion Projects of Beijing Municipal Commission for Health and Family Planning Health (2015-TG-15); High Level Health Technical Talent Training Program of Beijing Municipal Commission for Health and Family Planning Health (2015-3-023);
Beijing Talent Youth Training Program; The Priming Scientific Research Foundation for the Senior Researcher in Beijing Tongren Hospital, Capital Medical University (2015-YJJ-GGL-011) |
Corresponding Authors:
Jing Fu, Department of Ophthalmology, Beijing Tongren Hospital of Capital Medical University, Beijing 100730, China (Email: fu_jing@126.com)
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[1] |
王立华, 陈巍, 冯晶晶, 等. 674例3~6岁视力低常儿童屈光状态分析. 中华眼视光学与视觉科学杂志, 2017, 19(3): 168-171. DOI: 10.3760/cma.j.issn.1674-845X. 2017.03.009.
|
[2] |
Elflein HM, Fresenius S, Lamparter J, et a1. The prevalence of amblyopia in Germany: data from the prospective, population-based Gutenberg Health Study. Dtsch Arztebl Int, 2015, 112(19):338-344. DOI: 10.3238/arztebl.2015.0338.
|
[14] |
Press LJ. Relationship between anisometropia, amblyopia, and binocularity. Optom Vis Sci, 1999, 76(10): 677.
|
[16] |
Somer D, Budak K, Demirci S, et al. Against-the-rule (ATR) astigmatism as a predicting factor for the outcome of amblyopia treatment. Am J Ophthalmol, 2002, 133(6): 741-745.
|
[17] |
Atilla H, Erkam N. Comparison of anisometropes with and without amblyopia. Indian J Ophthalmol, 2011, 59(3): 215-216.DOI: 10.4103/0301-4738.81035.
|
[18] |
曾晓波, 许江涛. 儿童散光与子午线弱视. 中国斜视与小儿眼科杂志, 2016, 24(2): 48. DOI: 10.3969/J.ISSN.1005-328X.2016.02.016.
|
[15] |
严宏. 弱视. 北京: 科学出版社, 2007: 10.
|
[3] |
Sen DK. Anisometropic amblyopia. J Pediatric Ophthalmol Strabismus, 1980, 17(3): 180-184.
|
[4] |
李林, 孙省利, 卢炜. 近视性屈光参差与双眼视功能相关性的临床观察. 眼科, 2006, 15(5): 324-326.
|
[5] |
姚雪辉, 管永清, 夏春晓. 间歇性外斜视眼位控制力与双眼视觉关系研究. 中国实用眼科杂志, 2014, 32(3): 327-329. DOI:10.3760/cma.j.issn.1006-4443.2014.03.018.
|
[6] |
中华医学会眼科分会斜弱视与小儿眼科学组. 弱视诊断专家共识(2011年). 中华眼科杂志, 2011, 47(8): 768. DOI: 10.3760/cma.j.issn.0412-4081.2011.08.027.
|
[7] |
Tong L, Saw SM, Chia KS, et a1. Anisometropia in Singapore school children. Am J Ophthalmol, 2004, 137(3): 474-479. DOI:10.1016/j.ajo.2003.10.028.
|
[8] |
罗俊, 王平. 屈光参差性弱视的研究. 国际眼科杂志, 2011,11(10): 1743-1745. DOI: 10.3969/j.issn.1672-5123.2011.10.018.
|
[9] |
Lin L, Lan W, Liao Y, et al. Treatment outcomes of myopic anisometropia with 1% atropine: a pilot study. Optom Vis Sci, 2013,90(12): 1486-1492. DOI: 10.1097/OPX.0000000000000097.
|
[16] |
Somer D, Budak K, Demirci S, et al. Against-the-rule (ATR) astigmatism as a predicting factor for the outcome of amblyopia treatment. Am J Ophthalmol, 2002, 133(6): 741-745.
|
[17] |
Atilla H, Erkam N. Comparison of anisometropes with and without amblyopia. Indian J Ophthalmol, 2011, 59(3): 215-216.DOI: 10.4103/0301-4738.81035.
|
[10] |
Ying GS, Huang J, Maguire MG, et al. Associations ofanisometropia with unilateral amblyopia, interocular acuity difference, and stereoacuity in preschoolers. Ophthalmology,
|
[18] |
曾晓波, 许江涛. 儿童散光与子午线弱视. 中国斜视与小儿眼科杂志, 2016, 24(2): 48. DOI: 10.3969/J.ISSN.1005-328X.2016.02.016.
|
20 |
13, 120(3): 495-503. DOI: 10.1016/j.ophtha.2012.08.014.
|
[11] |
Oguz H, Oguz V. The effects of experimentally induced anisometropia on stereopsis. J Pediatr Ophthalmol Strabismus,2000, 37(4): 214-218.
|
[12] |
Brooks SE, Johnson D, Fischer N. Anisometropia and binocularity. Ophthalmology, 1996, 103(7): 1139-1143.
|
[13] |
亢晓丽, 郭秀荣. 儿童屈光参差与弱视、立体视相关性的研究. 中国实用眼科杂志, 2004, 22(7): 519-522.
|
[14] |
Press LJ. Relationship between anisometropia, amblyopia, and binocularity. Optom Vis Sci, 1999, 76(10): 677.
|
[15] |
严宏. 弱视. 北京: 科学出版社, 2007: 10.
|
[16] |
Somer D, Budak K, Demirci S, et al. Against-the-rule (ATR) astigmatism as a predicting factor for the outcome of amblyopia treatment. Am J Ophthalmol, 2002, 133(6): 741-745.
|
[17] |
Atilla H, Erkam N. Comparison of anisometropes with and without amblyopia. Indian J Ophthalmol, 2011, 59(3): 215-216.DOI: 10.4103/0301-4738.81035.
|
[18] |
曾晓波, 许江涛. 儿童散光与子午线弱视. 中国斜视与小儿眼科杂志, 2016, 24(2): 48. DOI: 10.3969/J.ISSN.1005-328X.2016.02.016.
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