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Artificial Intelligence Analysis of Fundus Images—Opportunities and Challenges |
Wenqiu Wang 1, 2, 3, Xiaodong Sun 1, 2, 3 |
1 Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080, China 2 Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai 200080, China 3 Shanghai Key Laboratory of Fundus Diseases, Shanghai 200080, China |
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Abstract Medical imaging technology plays an important role in the screening, evaluation, diagnosis, and monitoring of fundus diseases. In recent years, the development of multi-modality imaging fusion technology, image databases, standardized protocols and image analysis have extracted large amounts of information from imagebased features. Artificial intelligence applications in fundus imaging will bring new opportunities for increasing the rate of disease diagnosis, accelerating the development of new drugs, promoting research and development, improving diagnosis and treatment, and judging the prognosis of patients. This review covers the research status, difficulties and trends of the combination of artificial intelligence and fundus imaging, as well as taking China's national status into consideration, with the goal of presenting an objective update on relevant topics and new prospects in this field.
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Received: 10 October 2018
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Fund: Key Program of National Natural Science Foundation of China (81730026); Key Projects of Pharmacognosy of Shanghai Science and Technology Commission Foundation (17411953000); Shanghai Pujiang Program (18PJ1409500) |
Corresponding Authors:
Xiaodong Sun, Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080, China; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai 200080, China; Shanghai Key Laboratory of Fundus Diseases, Shanghai 200080, China (Email: xdsun@sjtu.edu.cn)
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[1] |
韩丁, 吴淑英, 李筱荣, 等. 中老年人视觉损害的流行病学
|
|
调查. 中华眼视光学与视觉科学杂志, 2013, 15(1): 61-64.
|
|
DOI: 10.3760/cma.j.issn.1674-845X.2013.01.017.
|
[2] |
孙心铨, 刘晓玲. 眼底疾病影像学检查的合理应用及联合
|
|
应用. 中华眼视光学与视觉科学杂志, 2011, 13(3): 161-164.
|
|
DOI: 10.3760/cma.j.issn.1674-845X.2011.03.001.
|
[3] |
唐东润. 眼科影像学在临床上的应用及其特点. 中华眼视光
|
|
学与视觉科学杂志, 2014, 16(11): 641-645. DOI: 10.3760/cma.
|
|
j.issn.1674-845X.2014.11.001.
|
[4] |
中华医学会眼科学会眼底病学组. 我国糖尿病视网膜病变临
|
|
床诊疗指南(2014年). 中华眼科杂志, 2014, 50(11): 851-865.
|
|
DOI: 10.3760/cma.j.issn.0412-4081.2014.11.014.
|
[5] |
Gulshan V, Peng L, Coram M, et al. Development and validation
|
|
of a deep learning algorithm for detection of diabetic retinopathy
|
|
in retinal fundus photographs. JAMA, 2016, 316(22): 2402-
|
24 |
10. DOI: 10.1001/jama.2016.17216.
|
[6] |
Abràmoff MD, Lou Y, Erginay A, et al. Improved automated
|
|
detection of diabetic retinopathy on a publicly available dataset
|
|
through integration of deep learning. Invest Ophthalmol Vis Sci,
|
20 |
16, 57(13): 5200-5206. DOI: 10.1167/iovs.16-19964.
|
[7] |
Kermany DS, Goldbaum M, Cai W, et al. Identifying medical
|
|
diagnoses and treatable diseases by image-based deep learning.
|
|
Cell, 2018, 172(5): 1122-1131.e9. DOI: 10.1016/j.cell.2018.02.
|
|
010.
|
[8] |
Raju M, Pagidimarri V, Barreto R, et al. Development of a
|
|
deep learning algorithm for automatic diagnosis of diabetic
|
|
retinopathy. Stud Health Technol Inform, 2017, 245: 559-563.
|
[9] |
Xiao S, Bucher F, Wu Y, et al. Fully automated, deep learning
|
|
segmentation of oxygen-induced retinopathy images. JCI
|
|
Insight, 2017, 2(24). pii: 97585. DOI: 10.1172/jci.insight.97585.
|
[10] |
Welikala RA, Foster PJ, Whincup PH, et al. Automated arteriole
|
|
and venule classification using deep learning for retinal images
|
|
from the UK Biobank cohort. Comput Biol Med, 2017, 90: 23-
|
32 |
DOI: 10.1016/j.compbiomed.2017.09.005.
|
[11] |
Rahimy E. Deep learning applications in ophthalmology. Curr
|
|
Opin Ophthalmol, 2018, 29(3): 254-260. DOI: 10.1097/ICU.
|
00 |
00000000000470.
|
[12] |
陈浙一, 黄美娜. 基于职业倦怠调查表研究眼视光医学教育
|
|
体系下视光医师与眼科医师的职业倦怠状况及其相关因素.
|
|
中华眼视光学与视觉科学杂志, 2017, 19(8): 496-501. DOI:
|
10 |
3760/cma.j.issn.1674-845X.2017.08.008.
|
[13] |
杨晓慧, 胡爱莲. 《糖尿病视网膜病变分级诊疗服务技术方案》
|
|
解读. 中华全科医师杂志, 2017, 16(8): 577-578. DOI: 10.3760/
|
|
cma.j.issn.1671-7368.2017.08.001.
|
[14] |
张秀兰, 李飞. 人工智能和青光眼: 机遇与挑战. 中华实验眼
|
|
科杂志, 2018, 36(4): 245-247. DOI: 10.3760/cma.j.issn.2095-
|
01 |
60.2018.04.002.
|
|
|
|