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Investigation of Myopic Maculopathy Classification and Its Relationship with Retinoschisis in Highly Myopic Eyes |
Ruoshi Wang, Minlu Song, Xiaohan Wang, Tong Li, Fenghua Wang, Xiaodong Sun |
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China |
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Abstract Objective: To study the correlation between retinoschisis and different types of fundus disease in high myopia and evaluate the different types of morphologic characteristics in highly myopic eyes. Methods:In this retrospective study, 116 patients (174 eyes) with high myopia from the outpatient department were included from October 2015 to December 2017. All participants underwent standardized medical interviews and ophthalmic examinations. An independent samples t test or one-way ANOVA were used to compare the measurement data. A chi square test (Fisher's exact probability method) was used to compare the numerical data. Results: There were five types of fundus disease shown on the fundus photographs: C0, no macular lesions in 10 eyes; C1, tessellated fundus in 74 eyes; C2, diffuse chorioretinal atrophy in 36 eyes; C3, patchy chorioretinal atrophy in 25 eyes and C4, macular atrophy in 29 eyes. Retinoschisis was detected in 70 eyes (40%) among eyes with C1, 2, 3, and 4, and the incidence of retinoschisis was highest in C2 (58%). Conclusions: The International Classification based on fundus color photography combined with OCT shows the highest prevalence of retinoschisis in highly myopia patients with diffuse chorioretinal atrophy
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Received: 27 November 2018
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Fund: Project of Science and Technology Commission of Shanghai Municipality (16411952900); Shanghai Municiple Education Commission-Gaofeng Clinical Medicine Grant Support (20152229); Shanghai Engineering Center for Visual Science and Photomedicine (16dz2251500) |
Corresponding Authors:
Xiaodong Sun, Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China (Email: xdsun@sjtu.edu.cn)
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