Changes in higher-order aberrations in the anterior and posterior corneal surfaces and total cornea after 2 mm micro-incision SMILE and 3-5 mm SMILE
Li Xiaojing,Wang Yan,Dou Rui,Zhang Jiamei,Li Hua
Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Clinical College of Ophthalmology Tianjin Medical University, Tianjin 300020, China
Objective To evaluate the changes in higher order aberrations in the anterior and posterior corneal surfaces and the total cornea after 2 mm micro-incision small incision lenticule extraction (SMILE) and 3-5 mm SMILE. Methods Sixty-one subjects (61 eyes) were enrolled in this prospective study. Although the surgery was performed on both eyes, only the right eyes were chosen for analysis. Two mm micro-incision SMILE surgery was performed on 26 subjects and SMILE surgery with an incision ranging from 3-5 mm was performed on another 35 subjects. Aberrations on the anterior and posterior corneal surfaces and total corneal aberrations were measured by Pentacam topography preoperatively and 1 month and 6 months postoperatively. Twenty subjects (20 eyes) who underwent the 2 mm SMILE surgery remained after 6 months and all 35 subjects (35 eyes) who underwent the 3-5 mm SMILE surgery remained. Repeated ANOVA was used to compare the Zernike coefficients of the corneal aberrations before and after surgery. The difference in aberrations between the 2 mm and 3-5 mm SMILE groups was compared with an independent t test. Results In the 2 mm SMILE group, the total higher order aberrations (tHOA), vertical coma (Z3-1), horizontal coma (Z31) and spherical aberrations (Z40) for the anterior corneal surface and total corneal had increased significantly 1 month and 6 months postoperatively (all at P<0.05). There were significant differences in Z3-1 and Z40 for the posterior corneal surface postoperatively compared with preoperative values (all at P<0.05). While in the 3-5 mm SMILE group, significant differences were found in tHOA, Z3-1, Z31 and Z40 for the anterior and posterior corneal surfaces and the complete cornea at various follow-up visits (all at P<0.01). Differences in the anterior corneal surface between the 2 mm SMILE and 3-5 mm SMILE groups were found in tHOA, Z3-1, Z31 at 1 month and 6 months postoperatively (t1 m=3.509, -4.103, 2.418, all at P<0.05, t6 m=2.248, -2.628, 2.617, all at P<0.05). There was a significant difference in Z31 for the posterior corneal surface between the two groups at 1 month and 6 months postoperatively (t=-2.416, -2.852, all at P<0.05). The difference in total corneal aberrations between the two groups was noted for tHOA, Z3-1 and Z31 1 month after surgery (t=2.376, -3.323, 2.623, all at P<0.05). Conclusion Different changes in aberrations of the anterior and posterior corneal surfaces and total cornea were noted after 2 mm and 3-5 mm SMILE surgery. There was no significant difference in total corneal aberrations between the 2 mm and 3-5 mm SMILE groups for tHOA, Z3-1, Z31 and Z40 at 6 months postoperatively. The influence of 2 mm micro-incision SMILE on the posterior corneal surface was relatively slight compared with that for the 3-5 mm SMILE group.
李晓晶,王雁,窦瑞,张佳媚,李华. 2 mm微切口与3~5 mm切口SMILE术后角膜高阶像差的比较[J]. 中华眼视光学与视觉科学杂志, 2015, 17(10): 609-613.
Li Xiaojing,Wang Yan,Dou Rui,Zhang Jiamei,Li Hua. Changes in higher-order aberrations in the anterior and posterior corneal surfaces and total cornea after 2 mm micro-incision SMILE and 3-5 mm SMILE. Chinese Journal of Optometry Ophthalmology and Visual science, 2015, 17(10): 609-613. DOI: 10.3760/cma.j.issn.1674-845X.2015.10.008
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