Objective To realize the storage of examination results, remote access, centralized management, a data collection scheme of digital inspection instrument which is in accordance with the clinical requirements of the Ophthalmology Department was developed. Methods According to the common clinical examination method in ophthalmology medical process, more than 20 different models, and different manufacturers of digital inspection instrument was selected to analysis, extraction and induction of the source data format, instrument interface and target data format. The general data collection model is abstracted finally. Results In practice, according to the design model, the digital acquisition system of ophthalmology department was constructed successfully. It was deployed more than 5 years in Eye Hospital of Wenzhou Medical Universtiy which has good effect on the collection and has good generality and expansibility. The system can meet the requirement of data collection of digital inspection instruments in the ophthalmology department, and support the flexible expansibility of the new varieties of instruments. Conclusion The output method and data format of the instruments in ophthalmology department was summarized in the scheme. There is a universal data collection scheme was established to improve the efficiency of information construction in ophthalmology department. The result of data meet majority of the requirement of the clinical diagnosis, then effectively solve the problem of "information island". "Examination in a place was shared in whole hospital" is achieved.