Primary angle closure glaucoma (PACG) is a kind of common disease causing irreversible blindness. The traditional risk factors of the characteristic features of angle closure glaucoma include not only some static anatomical factors such as: shallower anterior chamber, shorter axial length and thicker lens, but also some dynamic factors including iris dynamic change, choroidal expansion. With the development of the technology of Ophthalmological iconography, more anatomical structures in the closure angle can be observed more carefully. Among them, the iris and choroid, which play important roles in PACG should be paid more attention. With the new techniques such as AS-OCT (anterior segment optical coherence tomographyanterior segment optical coherence tomography), we can summarize some new comprehension of the mechanism of angle closure, in order to clarify the relation between iris, choroid and angle closure, thus to make better guidance for early diagnosis and personalized treatment of angle closure glaucoma.
张莹,吴作红. 虹膜脉络膜在闭角型青光眼中的作用机制研究进展. 中华眼视光学与视觉科学杂志, 2016, 18(8):508-512. DOI:10.3760/cma.j.issn.1674-845X.2016.08.014.
Zhang Ying,Wu Zuohong. The research progress of the iris choroid mechanism in angle-closure glaucoma. Chinese Journal of Optometry Ophthalmology and Visual science, 2016, 18(8):508-512.
Wang B, Sakata LM, Friedman DS, et al. Quantitative iris parameters and associations with narrow angles[J]. Opthalmology,2010,117(1):11-17. DOI:10.1016/j.ophtha.2009.06.017.
Shabana N, Aquino MC, See J, et al. Quantitative evaluation of anterior chamber parameters using anterior segment optical coherence tomography in primary angle closure mechanisms[J]. Clin Experiment Ophthalmol,2012,40(8):792-801. DOI:10.1111/j.1442-9071.2012.02805.x.
[10]
Silver DM, Quigley HA. Aqueous flow through the iris-lens channel: estimates of differential pressure between the anterior and posterior chambers[J]. J Glaucoma,2004,13(2):100-107.
Tarongoy P, Ho CL, Walton DS. Angle-closure glaucoma: The role of the lens in the pathogenesis, prevention, and treatment[J]. Surv Opthalmol,2009,54(2):211-225. DOI:10.1016/j.survophthal.2008.12.002.
[13]
Liu J, Lamba T, Belyea DA. Peripheral laser iridoplasty opens angle in plateau iris by thinning the cross-sectional tissues[J]. Clin Ophthalmol,2013,7:1895-1897. DOI:10.2147/OPTH.S47297.
Gohdo T, Tsumura T, Lijima H, et al. Ultrasound biomicroscopic study of ciliary body thickness in eyes with narrow angles[J].Am J Opthalmol,2000,129(3):342-346.
[20]
李凤鸣. 眼科全书[M]. 北京:人民卫生出版社,1996:138-150.
[21]
Arora KS, Quigley HA. Author response: Choroidal thickness change after water drinking is greater in angle closure than in open-angle eyes[J]. Invest Ophthalmol Vis Sci,2013,54(1):657-658. DOI:10.1167/iovs.12-11557.
[22]
Schuman JS, Massicotte EC, Connolly S, et al. Increased intraocular pressure and visual field defects in high resistance wind instrument players[J]. Ophthalmology,2000,107(1):127-133.
[23]
Zhou M, Wang W, Ding X, et al. Choroidal thickness in fellow eyes of patients with acute primary angle-closure measured by enhanced depth imaging spectral-domain optical coherence tomography[J]. Invest Ophthalmol Vis Sci,2013,54(3):1971-1978. DOI:10.1167/iovs.12-11090.
[24]
Banitt M. The choroid in glaucoma[J]. Curr Opin Ophthalmol,2013,24(2):125-129. DOI:10.1097/ICU.0b013e32835d9245.
[25]
Arora KS, Jefferys JL, Maul EA, et al. Choroidal thickness change after water drinking is greater in angle closure than in open angle eyes[J]. Invest Ophthalmol Vis Sci,2012,53(10):6393-6402. DOI:10.1167/iovs.12-10224.
Bellows AR, Chylack LT, Hutchinson BT. Choroidal detachment. Clinical manifestation therapy and mechanism of formation[J]. Ophthalmology,1981,88(11):1107-1115.
[28]
Quigley HA. What′s the choroid got to do with angle closure[J]. Arch Ophthalmol,2009,127(5):693-694. DOI:10.1001/archophthalmol.2009.80.
[29]
Arora KS, Jefferys JL, Maul EA, et al. The choroid is thicker in angle closure than in open angle and control eyes[J]. Invest Ophthalmol Vis Sci,2012,53(12):7813-7818. DOI:10.1167/iovs.12-10483.
Sakai H, Morine-Shinjyo S, Shinzato M, et al. Uveal effusion in primary angle-closure glaucoma[J]. Ophthalmology,2005,112(3): 413-419. DOI:10.1016/j.ophtha.2004.08.026.
[32]
Kumar RS, Quek D, Lee KY, et al. Confirmation of the presence of uveal effusion in Asian eyes with primary angle closure glaucoma: an ultrasound biomicroscopy study[J]. Arch Opthalmol,2008,126(12):1647-1651. DOI:10.1001/archophthalmol.2008.514.
Yang M, Aung T, Husain R, et al. Choroidal expansion as a mechanism for acute primary angle closure: an investigation into the change of biometric parameters in the first two weeks[J]. Br J Ophthalmol,2005,89(3):288-290. DOI:10.1136/bjo.2004.048686.
[35]
Banta JT, Hoffman K, Budenz DL, et al. Presumed topirmate-induced bilateral acute angle-closure glaucoma[J]. Am J Ophthalmol,2001,132(1):112-114.
[36]
Bernadino CR, Davidson RS, Maus M, et al. Angle-closure glaucoma in association with orbital pseudotumor[J]. Ophthalmology,2001,108(9):1603-1606.
[37]
Lombard C, Saulnier J, Wallach J. Assays of matrix metalloproteinases (MMPS) activities: a review[J]. Biochimie,2005, 87(3-4):265-272. DOI:10.1016/j.biochi.2005.01.007.
[38]
Gentle A, Liu Y, Martin JE, et al. Collagen gene expressionand thealtered accumulation of sclera collagen during thedevelopment of high myopia[J]. J Biol chem,2003,278(19):16587-16594. DOI: 10.1074/jbc.M300970200.
Quigley HA. Angle-closure glaucoma-simpler answers to complex mechanisms: LXVI Edward Jackson Memorial Lecture[J]. Am J Opthalmol,2009,148(5):657-669 e651. DOI:10.1016/j.ajo.2009.08. 009.