Abstract: Objective: To evaluate the feasibility of IOLMaster 700 in clinical application by analyzing the ocular related biometric parameters measured by IOLMaster 700 and compared with those of Lenstar LS900 in cataract patients. Methods: In this case series study, 71 cataract patients who underwent optical biometry in Foshan Second People's Hospital were enrolled from September to October 2019. Biometric parameters measured both by the IOLMaster 700 and Lenstar LS900 were compared. The axial length (AL), anterior chamber (ACD), lens thickness (LT), white to white (WTW), and mean corneal curvature (Km) were measured. Paired t test was used to compare the differences of the parameters. Bland-Altman plots were used to analyze the consistency. McNemar test was used to analyze the detection rate of AL. Results: There was no significant difference in AL and Km between IOLMaster 700 and Lenstar LS900 (t=1.728, P=0.088; t=0.804, P=0.424). There were significant differences in ACD, LT and WTW between the two biometers (t=-5.862, P<0.001; t=3.333, P=0.001; t=4.709, P<0.001). AL, ACD, LT, WTW and Km were not consistent. The detection rate of AL measured by IOLMaster 700 was higher than that by Lenstar LS900 (P=0.016). Conclusions: The IOLMaster 700 measurements do not show good consistency with those of Lenstar LS900 in clinical cataract patients. However the IOLMaster 700 has a lower detection failure rate in AL.
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