Comparative on Refractive Development of Preschool Children with High Hyperopia and Low Hyperopia
Lijun Wang, Nan Wei, Yuxian Ning, Jing Li, Xuehan Qian
Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital; Tianjin Key Laboratory of Retinal Functions and Diseases; Tianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Tianjin 300384, China
Abstract:Objective: To compare the characteristics of refractive development in preschoolers with high hyperopia and low hyperopia. Method: In this retrospective case-series study, a total of 43 preschool children (86 eyes) with hypermetropia who were admitted to Tianjin Medical University Eye Hospital from July 2020 to December 2021 were enrolled. According to the results of spherical diopter after ciliary paralysis, the children were divided into two groups: high hyperopia group 27 cases with 54 eyes and low hyperopia group 16 cases with 32 eyes.Recording the diopter and eye biologic parameters including axial length (AL), corneal curvature radius, axial length/corneal radius of curvature at baseline and follow-up of one year.Intra-group diopter and eye biological parameters were analyzed by self paired t test. Intra-group best corrected visual acuity was compared by Wilcoxon signed rank test. Independent sample t test was used to analyze the difference of changes in eye biological parameters between groups. Results: The annual decrease of equivalent spherical equivalent (SE) in high hyperopia group was (0.72±0.41)D (t=-9.26, P<0.001), compared to baseline (8.37±1.84)D. The difference of annual growths of AL in high hyperopia group [(0.31±0.18)mm] and low hyperopia group [(0.21±0.09)mm] was statistically significant (t=3.53, P=0.001). There was no significant difference between the annual changes of corneal curvature radius in the two groups. The annual increases of AL/corneal radius of curvature in high hyperopia group (0.04±0.02) was significantly different from that in low hyperopia group (0.02±0.03) (t=3.23, P=0.002). Conclusion: Compared with preschool children with low hyperopia, the annual increase of AL and AL/corneal radius of curvature was larger in preschool children with high hyperopia, suggesting that it is necessary to follow up children with high hyperopia closely.
王丽俊, 魏楠, 宁玉贤, 等.. 学龄前高度远视和低度远视儿童屈光发育比较[J]. 中华眼视光学与视觉科学杂志, 2022, 24(7): 536-540.
Lijun Wang, Nan Wei, Yuxian Ning,et al. Comparative on Refractive Development of Preschool Children with High Hyperopia and Low Hyperopia. Chinese Journal of Optometry Ophthalmology and Visual science, 2022, 24(7): 536-540. DOI: 10.3760/cma.j.cn115909-20211212-00484
Guo X, Fu M, Ding X, et al. Significant axial elongation with minimal change in refraction in 3- to 6-year-old Chinese preschoolers: the Shenzhen Kindergarten Eye Study. Ophthalmology, 2017, 124(12): 1826-1838. DOI: 10.1016/ j.ophtha.2017.05.030.
[2]
Jiang X, Tarczy-Hornoch K, Stram D, et al. Prevalence, characteristics, and risk factors of moderate or high hyperopia among multiethnic children 6 to 72 months of age. Ophthalmology, 2019, 126(7): 989-999. DOI: 10.1016/ j.ophtha.2019.02.021.
[3]
Kulp MT, Ying G, Huang J, et al. Associations between hyperopia and other vision and refractive error characteristics. Optom Vis Sci, 2014, 91(4): 383-389. DOI: 10.1097/ OPX.0000000000000223.
[4]
Tarczy-Hornoch K, Varma R, Cotter SA, et al. Risk factors for decreased visual acuity in preschool children. Ophthalmology, 2011, 118(11): 2262-2273. DOI: 10.1016/j.ophtha.2011.06.033.
[5]
Cotter SA, Varma R, Tarczy-Hornoch K, et al. Risk factors associated with childhood strabismus. Ophthalmology, 2011, 118(11): 2251-2261. DOI:10.1016/j.ophtha.2011.06. 032.
[6]
Hu Y, Ding X, Zeng J, et al. Longitudinal changes in spherical equivalent of moderate to high hyperopia: 2- to 8-Year Followup of children at an initial age of 5.5 to 8.4 years. Invest Ophthalmol Vis Sci, 2019, 60(8): 3127-3134. DOI: 10.1167/ iovs.18-26435.
[7]
Mezer E, Meyer E, Wygnansi-Jaffe T, et al. The long-term outcome of the refractive error in children with hypermetropia. Graefes Arch Clin Exp Ophthalmol, 2015, 253(7): 1013-1019. DOI: 10.1007/s00417-015-3033-z.
Mutti DO, Sinnott LT, Lynn Mitchell G, et al. Ocular component development during infancy and early childhood. Optom Vis Sci, 2018, 95(11): 976-985. DOI: 10.1097/OPX.0000000000001296.
[10]
Ip JM, Robaei D, Kifley A, et al. Prevalence of hyperopia and associations with eye findings in 6- and 12-year-olds. Ophthalmology, 2008, 115(4): 678-685. DOI: 10.1016/ j.ophtha.2007.04.061.
[11]
Ohlsson J, Baumann M, Sjostrand J. Longterm refractive and visual outcomes in subjects with high hyperopia. Acta Ophthalmol Scand, 2004, 82(4): 486-487. DOI: 10.1111/j.1395- 3907.2004.00287.x.
Chen W, Chen J, Zhang F, et al. Visual outcome in isoametropic amblyopic children with high hyperopia and the effect of therapy on retinal thickness. Am J Ophthalmol, 2013, 155(3): 536-543. DOI: 10.1016/j.ajo.2012.09.028.
[15]
Ma Y, Lin S, Morgan IG, et al. Eyes grow towards mild hyperopia rather than emmetropia in Chinese preschool children. Acta Ophthalmol, 2021, 99(8): e1274-e1280. DOI: 10.1111/ aos.14810.