B/F Ratio、中央角膜厚度对SimK和TCRP一致性的影响

doi:10.3760/cma.j.cn115909-20210523-00207

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摘要目的：分析正常角膜白内障患者角膜后前表面曲率半径之比（B/F Ratio）、中央角膜厚度（CCT）对模拟角膜屈光力（SimK）和全角膜屈光力（TCRP）一致性的影响。方法：回顾性系列病例研究。收集2019 年9 月至2020 年1 月在山西省眼科医院行超声乳化白内障联合人工晶状体（IOL）植入术的正常角膜白内障患者202 例的临床资料及术前Pentacam HR眼前段分析仪测量结果，包括瞳孔中央 4 mm区域内的角膜SimK、TCRP、B/F Ratio、CCT及SimK和TCRP差异△Km（△Km=SimK-TCRP）。若患者为单眼手术，则取手术眼的检查结果用于统计；若患者为双眼手术，则通过抛投硬币的方法，随机选择1 眼的检查结果用于统计。对Pentacam HR眼前段分析仪测量结果中SimK和TCRP数据进行配对样本t检验，并采用Pearson相关性分析CCT、B/F Ratio与△Km相关性，建立多重线性回归方程。结果：202 例患者角膜SimK、TCRP、△Km、B/F Ratio、CCT分别为（44.45±1.51）D、（44.34±1.59）D、（0.11±0.30）D、（82.04±1.52）%、（537±30）μm。△Km为0 D占比12.4%，SimK与 TCRP差异有统计学意义（t=5.22，P<0.001）。B/F Ratio、CCT与△Km呈负相关（r=-0.22，P<0.001； r=-0.17，P=0.014）；B/F Ratio、CCT与△Km多重线性回归方程为：△Km=6.882-6.549×B/F Ratio- 0.003×CCT（R2=0.13；F=14.90，P<0.001）。结论：SimK和TCRP之间存在差异，该差异与B/F Ratio、 CCT呈负相关。过小的B/F Ratio、CCT会使SimK高于TCRP，从而引起△Km远视漂移。

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	吴万民
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关键词 ：角膜, 全角膜屈光力, 中央角膜厚度, 角膜后前表面曲率半径比值

Abstract：Objective: To evaluate the effects of the back-front corneal radius ratio (B/F Ratio) and central corneal thickness (CCT) on the consistency of the simulated keratometry (SimK) and total corneal refractive power (TCRP) in normal corneal patients with cataract. Methods: This retrospective analysis focused on the clinical data of 202 patients with cataracts and a normal cornea who underwent phacoemulsification with intraocular lens implantation in Shanxi Eye Hospital from September 2019 to January 2020. Corresponding measurement results of preoperative Pentacam HR anterior segment analyzer were analyzed, including the corneal SimK, TCRP, B/F Ratio, CCT and △Km (△Km=SimK-TCRP), which is the difference between SimK and TCRP, in the central 4 mm area of the pupil. Only 1 eye from each patient was selected, and if the patient had binocular surgery, a random eye was chosen by tossing a coin. Then, a paired samples t-test on SimK and TCRP data was conducted on the measurement results of the Pentacam HR anterior segment analyzer. Pearson correlation analysis was applied to evaluate the correlation of CCT and B/F Ratio with △Km, followed by the establishment of the multiple linear regression equation. Results: The mean values of corneal SimK, TCRP, △Km, B/F Ratio and CCT in 202 patients were 44.45±1.51 D, 44.34±1.59 D, 0.11±0.30 D, 82.04%±1.52%, and 537±30 μm, respectively. △Km=0 D accounted for 12.4% of the difference between SimK and TCRP, which was significant (t=5.2, P<0.001). The B/F Ratio and CCT were negatively correlated with △Km (r=-0.22, P<0.001; r=-0.172, P=0.014). The linear regression equation of the B/F Ratio, CCT and △Km was △Km=6.882-6.549×B/F Ratio-0.003×CCT (R2=0.13; F=14.90, P<0.001). Conclusions: There is a divergence between SimK and TCRP, which is negatively correlated with the B/F Ratio and CCT. The SimK will exceed the TCRP which can cause the hyperopia shift based on △Km, if the B/F Ratio and CCT are too small.

Key words： cornea total corneal refractive power corneal thickness back-front corneal radius ratio

收稿日期: 2021-05-23

PACS:

基金资助:山西省眼科医院院内科研基金（Q201902）

通讯作者: 吴万民（ORCID：0000-0001-5717-6961），Email：603313473@qq.com

引用本文:

吴万民，柴飞燕，刘杰为.. B/F Ratio、中央角膜厚度对SimK和TCRP一致性的影响[J]. 中华眼视光学与视觉科学杂志, 2022, 24(3): 216-220. Wanmin Wu, Feiyan Chai, Jiewei Liu. The Influence of B/F Ratio and Central Corneal Thickness on the Consistency of SimK and TCRP. Chinese Journal of Optometry Ophthalmology and Visual science, 2022, 24(3): 216-220. DOI: 10.3760/cma.j.cn115909-20210523-00207

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https://www.cjoovs.com/CN/10.3760/cma.j.cn115909-20210523-00207 或 https://www.cjoovs.com/CN/Y2022/V24/I3/216

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