Abstract：Objective: To investigate the differences of intraoperative parameters and clinical effects between Catalys and LenSx femtosecond platform for femtosecond laser-assisted cataract surgery. Methods: This was a prospective randomized control study. A total of eighty-four cases (84 eyes) from Xiamen Eye Center of Xiamen University from December 2021 to March 2022 were included in this study by using simple random sampling method. And participants were divided into the Catalys group (42 cases) and the LenSx group (42 cases) by the lottery method. Indicators collected in this study were as follows: visual acuity and intraocular pressure (IOP) before the operation and at 1 day, 7 days, 1 month, and 3 months after operation, and intraoperative indicators (including interface docking times, suction-on time, anterior capsulotomy time, chop time, the number of anterior capsules with incomplete incision, the cases and quadrants involved (0-4) of the subconjunctival haemorrhage, cumulative dissipated energy (CDE), ultrasound time (UST), actual phacoemulsification time (APT), and effective phacoemulsification time (EPT). Student t-test, Chi-square test, and U test were used in this study to compare and analyze the differences in general data, femtosecond laser system intraoperative parameters, phacoemulsification intraoperative parameters and clinical effects between the two groups. Results: Gender, Age, and lens nucleus hardness had no statistically signifcant differences between the two groups (all P>0.05). However, in this study, suction-on time, anterior capsulotomy time, and chop time had significant differences (t=22.19、-28.95、10.15, all P<0.001). Meanwhile, statistically significant differences were observed between the two groups in postoperative IOP, the number of the subconjunctival haemorrhage, and the cumulative quadrant of subconjunctival haemorrhage on the first day after surgery (t=2.03, P=0.046; χ2=0.79, P=0.020; Z=-3.23, P=0.001). Additionally, this study showed that the docking times, the number of anterior capsules with incomplete incision, visual acuity before the operation and at 1 day, 7 days, 1 month, and 3 months after operation and IOP, CDE, UST, APT, EPT before the operation and at 7 days, 1 month, and 3 months after operation had no statistically significant differences (all P>0.05).Conclusions: The Catalys group had a lower risk of intraoperatively subconjunctival haemorrhage and faster anterior capsulotomy, while the LenSx group had shorter suction-on time and chop time.
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