Objective To understand the care and fitting habits of contact lens wearers; to evaluate perceptions about contact lens medical features based on Chinese questionnaires answered by experienced contact lens wearers; to try to develop tangible strategies to enhance the safety and comfort of contact lens wearers based on this information. Methods This study was based on an investigative survey. The survey was conducted in 42 big optical stores located in 6 cities: Shanghai,Beijing, Guangzhou, Shenzhen, Chengdu and Hangzhou. The survey targeted experienced wearers.The questionnaire consisted of 28 questions (6 parts) including: ①basic information and lens fitting history of wearers; ②current lens fitting behavior; ③daily lens care procedure; ④eye check and follow-up visits; ⑤assessment of perceptions about contact lenses; ⑥lens selection factors. Data were analyzed with chi-square tests. Results A total of 504 valid survey forms were collected. This study showed the following findings: ①Females, 439(87.1％) and males, 65(12.9％), age range of 19-42 years with an average age of (27.8±7.3)year. Experience with contact lens wear ranged from 6 months to 12 years,with an average of (6.3±5.2)years; ②6.2％(31/504) of the respondents reported that they slept with their daily wear lenses. The groups of a 2-week and 1-month replacement schedule were significantly more compliant than the groups with replacement schedule was daily, 3-6 month, ＞6 month disposable group (x2=12.32, 57.52, 45.91, P＜0.01). ③73.0％(368/504) washed their hands before handling the lenses, 54.0％(272/504) rubbed and cleaned the lenses, 38.1％(192/504) rinsed them with care solution; ④67.1％(338/504) indicated that they never proactively went for follow-up visits; 50.1％(207/413) and 38.1％(68/180) used an incorrect solution for discomfort and eye disease during the lens wear period; ⑤17.1％(86/504) knew that contact lenses were categorized as a medical device,over 60％ of the respondents had misunderstandings about contact lenses; ⑥63.1％ (318/504) took lens price